双相情感障碍与精神分裂症的神经电生理研究进展

Research Progress of Neuroelectrophysiology in Bipolar Disorder and Schizophrenia

摘要: 双相情感障碍及精神分裂症都是精神科常见疾病，二者之间症状存在重叠交叉，诊断容易混淆。患者发病后都可能出现认知，情感等多方面障碍。且二者都有着一定的自伤自残风险，对患者的社会功能也具有严重影响。因此对于此类疾病的早期识别和干预是极为重要的。而目前对于电子计算机与神经科学的结合使对于脑科学的研究也有了新的发展。事件相关电位，磁共振成像和人工神经网络的应用成为了针对各类神经精神疾病识别的重要课题。本片综述围绕探讨上述两种疾病的电生理学研究进展，进而提出更有针对性的病情评估策略，对未来精神障碍的诊断的客观化的依据提供线索。

Abstract: Bipolar disorder and schizophrenia are both common psychiatric disorders, and the symptoms overlap and overlap between the two, and the diagnosis is easily confused. Patients may develop cognitive, emotional, and other disorders after the onset of the disease. Both of them have a certain risk of self-injury and self-injury, and also have a serious impact on the social function of patients. Therefore, early identification and intervention of such diseases are extremely important. At present, the combination of computer science and neuroscience has led to new developments in the research of brain science. The application of event-related potentials, magnetic resonance imaging and artificial neural networks has become an important topic for the identification of various neuropsychiatric diseases. This review focuses on the progress of electrophysiology research on the above two diseases, and then proposes more targeted disease assessment strategies, so as to provide clues for the objectification of the diagnosis of mental disorders in the future.