髓鞘少突胶质细胞糖蛋白抗体相关疾病的研究进展
Research Progress of Myelin Oligodendrocyte Glycoprotein Antibody-Associated Diseases
摘要: 髓鞘少突胶质细胞糖蛋白抗体相关疾病(MOGAD)属于免疫介导的中枢神经系统炎性脱髓鞘疾病，各年龄段均可发病，可引起视神经、大脑、小脑、脑干、脊髓等部位脱髓鞘病变。随着检验技术的进步，MOGAD相应的诊断和管理的挑战也在不断扩大。本文将回顾总结MOGAD的流行病学，病理机制、临床表现、辅助检查、诊断与鉴别诊断、治疗预后等相关研究，旨在提高对该病的认识，从而早期识别、尽早治疗、减少复发。
Abstract: Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is an immune-mediated inflammatory demyelinating disease of the central nervous system, which can occur in all ages. It can cause demyelinating lesions in the optic nerve, brain, cerebellum, brain stem, spinal cord and other parts of the body. With the advancement of laboratory technology, the challenges in the diagnosis and management of MOGAD continue to expand. This article will review the epidemiology, pathological mechanism, clinical manifestations, auxiliary examination, diagnosis and differential diagnosis, treatment and prognosis of MOGAD, in order to improve the understanding of the disease, so as to early identification, early treatment and reduce recurrence.
文章引用：姜绍群, 曹洁. 髓鞘少突胶质细胞糖蛋白抗体相关疾病的研究进展[J]. 临床医学进展, 2024, 14(4): 282-289. https://doi.org/10.12677/acm.2024.1441019

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