Vgot-小柳–原田综合征1例并文献复习
Vogt-Koyanagi-Harada Syndrome: A Case Report and Literature Review
DOI: 10.12677/acm.2024.1441138, PDF,    科研立项经费支持
作者: 吕帅男*, 张 赫, 王玲玲#：北华大学附属医院神经内科，吉林 吉林
关键词: Vgot-小柳–原田综合征；病例报告；文献复习；Vogt-Koyanagi-Harada Syndrome； Case Reports； Literature Review
摘要: Vgot-小柳–原田综合征的眼内表现为双侧弥漫渗出性肉芽肿全葡萄膜炎，具有反复发作的临床特点，是一种难治性系统性自身免疫疾病，临床表现为头痛、眼葡萄膜炎、脑膜脑炎、中枢神经系统改变以及听觉异常，同时还伴随毛发改变和皮肤脱色素等，疾病尚无确切的发病机制，临床表现多不典型，极易误诊和漏诊。本文报道1例最初诊断为病毒性脑炎并以试验性治疗，最终确诊为Vgot-小柳–原田综合征，应及早规范应用激素以延缓病情进展，减少并发症，进而改善患者预后。
Abstract: The intraocular manifestations of Vgot-Koyanagi-Harada syndrome (VKHS) are bilateral diffuse exudative granuloma panuveitis with recurrent clinical characteristics. It is a refractory systemic autoimmune disease with clinical manifestations including headache, ocular uveitis, meningoencephalitis, central nervous system changes and hearing abnormalities, accompanied by hair changes and skin depigmentation. There is no exact pathogenesis of the disease, the clinical manifestations are atypical, and it is easy to misdiagnose and omission. In this paper, we report a case of viral encephalitis initially diagnosed and treated experimentally, and finally diagnosed as Vgot-Koyanagi-Harada syndrome. Early and standardized use of hormones should be used to delay the progression of the disease, reduce complications, and improve the prognosis of the patient.
文章引用：吕帅男, 张赫, 王玲玲. Vgot-小柳–原田综合征1例并文献复习[J]. 临床医学进展, 2024, 14(4): 1167-1173. https://doi.org/10.12677/acm.2024.1441138

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