同时性结肠多原发癌一例并文献复习

Multiple Primary Cancers of the Colon at the Same Time: A Case and Literature Review

摘要: 多原发癌(MPC)是一种较少见的肿瘤学现象，可累及多个器官或同一器官多个部位。本文报道一例83岁男性多原发结肠癌患者，患者因反复便秘五年余入院，术前结肠镜检查显示升结肠癌、乙状结肠息肉恶变，诊断为同时性结肠MPC，行腹腔镜右半结肠癌姑息切除术 回肠–横结肠侧侧吻合术治疗，术后病理回报升结肠溃疡型中分化管状腺癌、乙状结肠息肉恶变。本病例提示临床医师应提高对MPC的认识与重视，注意鉴别诊断，以免漏诊、误诊。

Abstract: Multiple primary cancer (MPC) is a rare phenomenon in oncology, which can involve multiple organs or multiple parts of the same organ. This paper reports an 83-year-old male patient with multiple primary colon cancer who was admitted to hospital for more than five years due to repeated constipation. The patient was diagnosed with simultaneous colon MPC after preoperative colonoscopy, which showed malignant transformation of elevated colon cancer and sigmoid polyp. He was treated with laparoscopic palliative resection of right colon cancer plus ileo-transverse colon anastomosis. Postoperative pathology showed ulcerative moderately differentiated tubular adenocarcinoma of the ascending colon and malignant polyp of the sigmoid colon. This case suggests that clinicians should improve the understanding of MPC and pay attention to the differential diagnosis to avoid missed diagnosis and misdiagnosis.