早产儿脑室内出血的治疗进展
Advances in Treatment of Intraventricular Hemorrhage in Premature Infants
DOI: 10.12677/acm.2024.1441198, PDF,    科研立项经费支持
作者: 王朋宇：内蒙古医科大学内蒙古临床医学院，内蒙古 呼和浩特；张晓军*：内蒙古自治区人民医院神经外科，内蒙古 呼和浩特
关键词: 早产儿；脑室内出血；治疗进展；Premature Infants； Intraventricular Hemorrhage； Treatment Progress
摘要: 脑室内出血(Intraventricular hemorrhage, IVH)是早产的主要并发症。IVH的幸存者通常患有脑积水和白质损伤。白质损伤归因于血液诱导的轴突和成熟少突胶质细胞前体损伤，导致髓鞘形成减少和轴突损失。脑积水是由于血凝块阻塞脑脊液循环、脑脊液产生增加、淋巴管所致。本文综述了IVH脑损伤的新机制，以及缓解IVH幸存者出血性脑白质损伤和脑积水的近期治疗方法。
Abstract: Intraventricular hemorrhage (IVH) is a major complication of preterm labor. Survivors of IVH often suffer from hydrocephalus and white matter damage. White matter damage was attributed to blood-induced axonal and mature oligodendrocyte precursor damage, resulting in decreased myelination and axonal loss. Hydrocephalus is due to blood clots blocking cerebrospinal fluid circulation, increased production of cerebrospinal fluid, lymphatics. This article reviews the new mechanism of IVH brain injury and the recent treatment methods to alleviate hemorrhagic white matter injury and hydrocephalus in IVH survivors.
文章引用：王朋宇, 张晓军. 早产儿脑室内出血的治疗进展[J]. 临床医学进展, 2024, 14(4): 1608-1611. https://doi.org/10.12677/acm.2024.1441198

参考文献

[1] Ballabh, P. (2010) Intraventricular Hemorrhage in Premature Infants: Mechanism of Disease. Pediatric Research, 67, 1-8. [Google Scholar] [CrossRef] 
[2] Pinto-Martin, J.A., Whitaker, A.H., Feldman, J.F., et al. (1999) Relation of Cranial Ultrasound Abnormalities in Low-Birthweight Infants to Motor or Cognitive Performance at Ages 2, 6, and 9 Years. Developmental Medicine and Child Neurology, 41, 826-833. [Google Scholar] [CrossRef] 
[3] Deger, J., Goethe, E., Lopresti, M., et al. (2021) Intraventricular Hemorrhage in Premature Infants: A Historical Review. World Neurosurgery, 153, 21-25. [Google Scholar] [CrossRef] [PubMed]
[4] Antoniuk, S. and Da Silva, R.V. (2000) Periventricular and Intraventricular Hemorrhage in the Premature Infants. Revista de Neurologia, 31, 238-243. [Google Scholar] [CrossRef] 
[5] Ellenbogen, J., Waqar, M. and Pettorini, B. (2016) Management of Post-Haemorrhagic Hydrocephalus in Premature Infants. Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia, 31, 30-34. [Google Scholar] [CrossRef] [PubMed]
[6] Kuo, M. (2020) Surgical Management of Intraventricular Hemorrhage and Posthemorrhagic Hydrocephalus in Premature Infants. Biomedical Journal, 43, 268-276. [Google Scholar] [CrossRef] [PubMed]
[7] Vohr, B. (2022) Neurodevelopmental Outcomes of Premature Infants with Intraventricular Hemorrhage across a Lifespan. Seminars in Perinatology, 46, 151594. [Google Scholar] [CrossRef] [PubMed]
[8] Lampe, R., Rieger-Fackeldey, E., Sidorenko, I., et al. (2020) Assessing Key Clinical Parameters before and after Intraventricular Hemorrhage in Very Preterm Infants. European Journal of Pediatrics, 179, 929-937. [Google Scholar] [CrossRef] [PubMed]
[9] Langley, E., Blake, S. and Coe, K. (2022) Recent Review of Germinal Matrix Hemorrhage-Intraventricular Hemorrhage in Preterm Infants. Neonatal Network: NN, 41, 100-106. [Google Scholar] [CrossRef] 
[10] Navidi, A., De Boissieu, P., Mannes, I., et al. (2022) Periventricular Hemorrhagic Infarction (PVHI) Associated with Intraventricular Hemorrhage (IVH) in Premature Infants: Outcome at 2 Years of Age. Archives de Pediatrie: Organe Officiel de la Societe Francaise de Pediatrie, 29, 459-466. [Google Scholar] [CrossRef] [PubMed]

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