肠道菌群代谢产物TMAO和冠心病的相关性研究
Correlation between Trimethylamine Oxide, a Metabolite of Intestinal Flora, and Coronary Heart Disease
摘要: 如今，人口老龄化及城镇化进程加速，经济水平在快速增长，人们养成许多不健康的生活方式，导致心血管疾病已经成为严重影响人们健康水平的重要危险因素，其中冠心病(CHD)患者占了很大比重，动脉粥样硬化(AS)是CHD主要的病理基础，导致AS形成有很多因素，比如肥胖、高血压、糖尿病、脂代谢异常、吸烟、熬夜等。近年来，有相关研究发现肠道菌群代谢物TMAO与动脉粥样硬化形成有很大相关性，通过探究其相关机制，如果能够早期检测TMAO水平并及时干预，或许能为CHD的诊断及诊治提供新的方向。
Abstract: Nowadays, with the acceleration of the aging of the population, urbanization and the development of economic level, people adopt many unhealthy lifestyle. Cardiovascular disease VB (CVD) has become a serious threat for healthy level of residents, in which coronary heart disease (CHD) patients account for a large proportion. Atherosclerosis (AS) is the main pathological basis of CHD, and there are many risk factors for the AS, such as obesity, hypertension, diabetes, abnormal lipid metabolism, smoking, staying up late and so on. In recent years, some related studies have found that a great correlation between TMAO, a metabolite of flora and AS. By exploring its related mechanism, if the level of TMAO can be detected early and intervened in time, it may be useful for diagnosis.
文章引用：李蓉, 吕晋琳. 肠道菌群代谢产物TMAO和冠心病的相关性研究[J]. 临床医学进展, 2024, 14(4): 1621-1628. https://doi.org/10.12677/acm.2024.1441200

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