玉苓代茶饮在健康管理中对高尿酸血症人群的疗效观察

Observation on the Therapeutic Effect of Yuling Daicha Drink in Health Management for People with Hyperuricemia

摘要: 目的：评估玉苓代茶饮在预防及治疗高尿酸血症(HUA)中降低尿酸的临床疗效，拟为治疗高尿酸血症的治疗提供新的依据和方法。方法：选取重庆市永川区中医院健康管理中心2021年6月~2022年6月期间，体检筛查结果显示为高尿酸的患者，共有100例，随机将其分成例数相同的对照组和观察组，在对照组中对患者实施生活指导，包括开展健康宣教、低嘌呤饮食、多喝水、禁止饮酒等措施以及开展常规治疗，治疗组则以此为基础，额外服用玉苓代茶饮，剂量：玉米须3克；土茯苓10克；车前子10克，一天一剂，泡水频服，均治疗8周，并于比较两组HUA患者服用第4周、8周后尿酸值的变化。结果：最终完成试验观察病例100例，对照组50例，观察组50例，入组时尿酸两组患者尿酸无明显差异，P > 0.05。组间比较时，治疗1月后，两组尿酸缓解情况无统计学差异，P > 0.05；治疗2月后，观察组尿酸缓解情况优于对照组，差异具有统计学意义，P < 0.05。组内比较时，经1个月及2个月的治疗周期后，两组的尿酸水平均呈现出下降趋势，P < 0.05。结论：玉苓代茶饮对于改善高尿酸血症患者的尿酸水平具有显著效果，有助于保护肾脏功能，疗效优于基础治疗。

Abstract: Objectives: This paper aims to evaluate the clinical efficacy of Yuling Daicha drink in reducing uric acid in the prevention and treatment of hyperuricemia (HUA), and provide new basis and methods for the treatment of hyperuricemia. Methods: From June 2021 to June 2022, a total of 100 patients with high uric acid were selected from the Health Management Center of Yongchuan District Traditional Chinese Medicine Hospital in Chongqing. They were randomly divided into a control group and an observation group with the same number of cases. In the control group, life guidance was provided to the patients, including health education, low purine diet, drinking more water, prohibition of alcohol consumption, and routine treatment. The treatment group, on this basis, took an additional dose of Yuling Dai tea drink, with a dosage of 3 grams of corn silk; 10 g of Poria cocos; 10 grams of Cheqianzi, one dose per day, soaked in water and taken frequently, were treated for 8 weeks, and the changes in uric acid levels were compared between two groups of HUA patients after 4 and 8 weeks of treatment. Results: 100 cases of experimental observation were ultimately completed, with 50 cases in the control group and 50 cases in the observation group. Uric acid in enrollment was not significantly different between the two groups, P > 0.05. When comparing between groups, there was no statistical difference in uric acid response after 1 month of treatment, P > 0.05; after 2 months of treatment, the observation group was better than the control group, and the difference was statistically significant, P < 0.05. For within-group comparison, uric acid levels showed a decreasing trend after 1 month and 2 months of treatment cycles, P < 0.05. Conclusions: Yuling Daicha Drink has a significant effect on improving uric acid levels in patients with hyperuricemia, helping to protect kidney function, and its efficacy is better than basic treatment.