慢性肾脏病血管钙化的相关研究进展
Progress of Research Related to Vascular Calcification in Chronic Kidney Disease
DOI: 10.12677/acm.2024.1441249, PDF,   
作者: 吴 静, 杨小娟*：延安大学附属医院肾内科，陕西 延安
关键词: 慢性肾脏病；钙化；心血管病；综述；Chronic Kidney Disease； Calcification； Cardiovascular Disease； Review
摘要: 心血管疾病(CVD)和慢性肾脏病(CKD)关系密切，近年来随着死亡率的增加，引起全球广泛的关注。血管钙化(VC)在CKD患者中极为常见。血管钙化有两种不同的表型，分为血管内膜钙化和中膜钙化。动脉钙化是CKD患者发生心血管疾病的主要病理机制，可显著增加慢性肾脏病患者心脑血管不良事件的发生率和全因死亡率，慢性肾脏病患者血管钙化的发病机制尚不完全清楚。因此，在本文中，我们将讨论慢性肾脏病患者动脉钙化的发病机制，为临床更好地防治血管钙化的发生提供依据。
Abstract: Cardiovascular disease (CVD) is closely related to chronic kidney disease (CKD), and in recent years, they have attracted worldwide attention as mortality rates have risen. Vascular calcification (VC) is common in patients with CKD. There are two distinct phenotypes of vascular calcification, one is intimal calcification and the other is medial calcification. Arterial calcification is the main pathological mechanism of cardiovascular disease in CKD patients. It can significantly increase the incidence of adverse cardiovascular and cerebrovascular events and all-cause mortality in chronic kidney disease patients, at present, the pathogenesis of vascular calcification in CKD patients is still not completely elucidated. Therefore, this article reviews the pathogenesis of arterial calcification in CKD patients, and to provide the basis for improved clinical management of vascular calcification.
文章引用：吴静, 杨小娟. 慢性肾脏病血管钙化的相关研究进展[J]. 临床医学进展, 2024, 14(4): 1947-1952. https://doi.org/10.12677/acm.2024.1441249

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