内镜下逆行阑尾炎治疗术治疗阑尾炎的疗效与安全性评估
Evaluation of the Efficacy and Safety of Endoscopic Retrograde Appendicitis Treatment for Appendicitis
摘要: 目的:评估内镜下逆行阑尾炎治疗术(ERAT)治疗阑尾炎的疗效及安全性。方法:将2021年3月至2023年6月间收治的112例阑尾炎患者纳入研究,根据治疗方法,分为内镜下逆行阑尾炎治疗组(ERAT)组和腹腔镜下阑尾切除术(LA)组,比较ERAT组与LA组的治疗效果、患者的术后恢复情况、并发症及随访情况等。结果:ERAT组中有5例患者插管失败,1例患者由于术后肠穿孔转入外科行腹腔镜下阑尾切除术,LA组中1例患者术中转为开腹阑尾切除术,与LA组相比,ERAT组的手术时间、白细胞恢复正常时间、术后出院时间、并发症率均明显更低。结论:ERAT作为一种新型的治疗阑尾炎的方法,虽然有可能复发,手术失败等风险,但也具有创伤小、可保留阑尾、并发症少等优势,是除了LA外的另一种治疗阑尾炎的选择。
Abstract: Objective: To evaluate the efficacy and safety of endoscopic retrograde appendectomy (ERAT) for the treatment of appendicitis. Method: 112 patients with appendicitis admitted between March 2021 and June 2023 were included in the study. According to the treatment method, they were divided into an endoscopic retrograde appendicitis treatment group (ERAT) and a laparoscopic appendectomy (LA) group. The treatment effect, postoperative recovery, complications, and follow-up of the ERAT group and the LA group were compared. Result: In the ERAT group, 5 patients failed intubation, 1 patient underwent laparoscopic appendectomy due to postoperative intestinal perforation, and 1 patient in the LA group underwent open appendectomy. Compared with the LA group, the ERAT group had significantly lower surgical time, white blood cell recovery time, postoperative discharge time, and complication rate. Conclusion: ERAT, as a novel method for treating appendicitis, may have risks such as recurrence and surgical failure, but it also has advantages such as minimal trauma, preservation of the appendix, and fewer complications. It is another choice for treating appendicitis besides LA.
文章引用:刘轩雨, 张浩. 内镜下逆行阑尾炎治疗术治疗阑尾炎的疗效与安全性评估[J]. 临床医学进展, 2024, 14(4): 2668-2673. https://doi.org/10.12677/acm.2024.1441344

参考文献

[1] Gianfranco, C., Riccardo, M., Andrea, T., et al. (2016) Epidemiology and Outcomes of Acute Abdominal Pain in a Large Urban Emergency Department: Retrospective Analysis of 5,340 Cases. Annals of Translational Medicine, 4, 362. [Google Scholar] [CrossRef] [PubMed]
[2] Stewart, B., Khanduri, P., McCord, C., et al. (2014) Global Disease Burden of Conditions Requiring Emergency Surgery. British Journal of Surgery, 101, e9-e22. [Google Scholar] [CrossRef] [PubMed]
[3] Nakhamiyayev, V., Galldin, L., Chiarello, M., et al. (2010) Laparoscopic Appendectomy Is the Preferred Approach for Appendicitis: A Retrospective Review of Two Practice Patterns. Surgical Endoscopy, 24, 859-864. [Google Scholar] [CrossRef] [PubMed]
[4] Flum, D.R., Morris, A., Koepsell, T., et al. (2001) Has Misdiagnosis of Appendicitis Decreased over Time? A Population-Based Analysis. JAMA, 286, 1748-1753. [Google Scholar] [CrossRef] [PubMed]
[5] Liu, B.R., Kong, L., Song, M.Y., et al. (2020) Endoscopic Retrograde Appendicitis Herapy: Current Status and Future Development in China. Gastrointestinal Endoscopy, 91, 268. [Google Scholar] [CrossRef
[6] 石明亮, 王晓磊, 李江琳, 等. 内镜逆行阑尾炎治疗术与腹腔镜阑尾切除术在治疗急性阑尾炎中的应用效果比较[J]. 现代医药卫生, 2022, 38(5): 819-822.
[7] Andersson, M., Kolodziej, B., Andersson, R.E., et al. (2017) Randomized Clinical Trial of Appendicitis Inflammatory Response Score-Based Management of Patients with Suspected Appendicitis: Appendicitis Inflammatory Response Score Based Management of Suspected Appendicitis. British Journal of Surgery, 104, 1451-1461. [Google Scholar] [CrossRef] [PubMed]
[8] Jones, P.F. (2001) Suspected Acute Appendicitis: Trends in Management over 30 Years. British Journal of Surgery, 88, 1570-1577. [Google Scholar] [CrossRef] [PubMed]
[9] 程蕴. 内镜下逆行阑尾炎治疗术治疗急性非复杂性阑尾炎的疗效观察及安全性分析[J]. 中国医疗器械信息, 2020, 26(2): 92-93.
[10] Girard-Madoux, M.J.H., Gomez de Agüero, M., Ganal-Vonarburg, S.C., et al. (2018) The Immunological Functions of the Appendix: An Example of Redundancy? Seminars in Immunology, 36, 31-44. [Google Scholar] [CrossRef] [PubMed]
[11] 厉英超, 米琛, 李伟之, 等. 内镜下逆行阑尾炎治疗术治疗急性非复杂性阑尾炎的疗效观察及安全性评估[J]. 中国内镜杂志, 2016, 26(3): 11-17.
[12] 祝孟川, 曾永娟, 刘登瑞, 等. 阑尾切除术与抗生素比较治疗急性单纯性阑尾炎疗效和安全性的Meta分析[J]. 中国循证医学杂志, 2017, 17(2): 188-194.
[13] Varadhan, K.K., Neal, K.R. and Lobo, D.N. (2012) Safety and Efficacy of Antibiotics Compared with Appendicectomy for Treatment of Uncomplicated Acute Appendicitis: Meta-Analysis of Randomised Controlled Trials. British Medical Journal, 344, e2156. [Google Scholar] [CrossRef] [PubMed]
[14] 侯振, 索岳尔, 穆剑锋, 等. 原发性阑尾肿瘤30例临床诊治分析[J]. 医学与哲学(B), 2017, 38(2): 55-56 69.