MAPK信号通路在银屑病发病机制中的研究进展
Research Progress on MAPK Signaling Pathway in Pathogenesis of Psoriasis
DOI: 10.12677/acm.2024.1441381, PDF,    科研立项经费支持
作者: 曹瑞琪:内蒙古医科大学研究生学院,内蒙古 呼和浩特;段 妍*:内蒙古自治区人民医院皮肤性病科,内蒙古 呼和浩特
关键词: 银屑病MAPK信号通路发病机制Psoriasis MAPK Signaling Pathway Pathogenesis
摘要: 银屑病是临床上一种常见的慢性炎症性反复发作性皮肤病,以角质形成细胞过度增殖、炎性细胞浸润、真皮血管新生为主要特征。银屑病发病机制尚不明确,遗传、免疫、环境等多种因素都可参与疾病进展。MAPK信号通路在银屑病病程中发挥重要作用。本文就MAPK信号通路在银屑病发病机制中的研究进展进行综述,为后续研究提供参考。
Abstract: Psoriasis is a common chronic inflammatory and recurrent skin disease, which is characterised by hyperproliferation of keratinocytes, inflammatory cell infiltration, and dermal neovascularisation. The pathogenesis of psoriasis is still unclear, and genetic, immune and environmental factors are involved in the disease progression, and the MAPK signaling pathway plays an important role in psoriasis. In this paper, we review the research progress of MAPK signaling pathway in the pathogenesis of psoriasis, and provide reference for subsequent research.
文章引用:曹瑞琪, 段妍. MAPK信号通路在银屑病发病机制中的研究进展[J]. 临床医学进展, 2024, 14(4): 2983-2991. https://doi.org/10.12677/acm.2024.1441381

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