眼针联合鱼腥草注射液超声雾化熏眼治疗干眼症的临床观察

Clinical Observation of Eye Acupuncture Combined with Houttuynia cordata Injection Ultrasonic Nebulization Eye Fumigation Therapy for Dry Eye Syndrome

摘要: 目的：评价眼针联合鱼腥草注射液超声雾化熏眼治疗干眼症的临床效果。方法：前瞻性选取2022.06~2023.12于我院眼科就诊的干眼症患者62例，采用随机数字表法分为治疗组和对照组，治疗组采用眼针联合鱼腥草注射液超声雾化熏眼，对照组采用单纯鱼腥草注射液超声雾化熏眼，每周治疗5天，连续治疗4周。比较两组治疗前后的眼表疾病指数(OSDI)、泪膜破裂时间(BUT)、泪液分泌试验(SIT)、泪河高度(TMH)及临床疗效。结果：两组患者治疗前OSDI、BUT、SIT、TMH基线水平无统计学差异(P > 0.05)。两组治疗后OSDI评分均下降，且治疗组OSDI评分显著低于对照组(P < 0.05)。两组治疗后BUT明显增加，且治疗组BUT明显高于对照组(P < 0.05)。两组治疗后SIT明显延长，且治疗组SIT较对照组延长更显著(P < 0.05)。两组治疗后TMH明显提高，且治疗组TMH明显高于对照组(P < 0.05)。经治疗后，治疗组临床总有效率明显高于对照组，差异具有统计学意义(P < 0.05)。结论：眼针联合鱼腥草注射液雾化熏眼治疗干眼症能够有效改善干眼症患者眼部症状，稳定泪膜状态，提高临床疗效。

Abstract: Objective: To evaluate the clinical efficacy of eye acupuncture combined with Houttuynia cordata injection ultrasonic nebulization eye fumigation therapy for treating dry eye syndrome. Methods: A total of 62 prospective dry eye syndrome patients who visited our ophthalmology department from June 2022 to December 2023 were selected. They were randomly divided into treatment group and control group using random number table method. The treatment group received eye acupuncture combined with Houttuynia cordata injection ultrasonic nebulization eye fumigation therapy, while the control group received simple Houttuynia cordata injection ultrasonic nebulization eye fumigation therapy. Treatment was administered five days a week for four consecutive weeks. The ocular surface disease index (OSDI), tear film break-up time (BUT), Schirmer I test (SIT), tear meniscus height (TMH), and clinical efficacy before and after treatment were compared between the two groups. Results: Before treatment, there were no statistically significant differences in baseline levels of OSDI, BUT, ST, and TMH between the two groups (P > 0.05). After treatment, OSDI scores decreased in both groups, with the treatment group showing significantly lower OSDI scores than the control group (P < 0.05). BUT significantly increased in both groups after treatment, with the treatment group exhibiting significantly higher BUT than the control group (P < 0.05). SIT significantly prolonged in both groups after treatment, with the treatment group showing a more significant prolongation of SIT compared to the control group (P < 0.05). TMH significantly increased in both groups after treatment, with the treatment group having significantly higher TMH than the control group (P < 0.05). After treatment, the overall clinical efficacy rate in the treatment group was significantly higher than that in the control group, with a statistically significant difference (P < 0.05). Conclusion: Eye acupuncture combined with Houttuynia cordata injection ultrasonic nebulization eye fumigation therapy effectively improves ocular symptoms, stabilizes tear film status, and enhances clinical efficacy in patients with dry eye syndrome.