中西医结合治疗重度溃疡性结肠炎验案1则
A Case Study on the Combined Treatment of Traditional Chinese and Western Medicine for Severe Ulcerative Colitis
DOI: 10.12677/tcm.2024.135136, PDF,   
作者: 宋静微, 施丽婕*:天津中医药大学第一附属医院,国家中医针灸临床医学研究中心,天津
关键词: 溃疡性结肠炎维多珠单抗卫阳郁滞验案Ulcerative Colitis Vedolizumab Deficiency of Yang Qi and Stagnation of Qi Case Study
摘要: 溃疡性结肠炎是一种可累及直肠和结肠的终身性炎症性疾病,常反复发作,并可导致多种并发症,严重影响患者的生存质量,近年来生物制剂的出现虽扩展了临床医生治疗溃疡性结肠炎的选择,但仍有很多患者对其应答不佳,在临床诱导应用时缓解率远未达最佳水平,中医药精准个体化的治疗在改善患者症状、减少复发率及不良反应、提高患者生存质量上有很大优势,本文主要介绍运用中药联合维多珠单抗治疗效果显著的慢性重度溃疡性结肠炎验案1则。
Abstract: Ulcerative colitis is a lifelong inflammatory disease that can affect the rectum and colon, often recurring and leading to various complications, which seriously affects the quality of life of patients. Although the emergence of biological agents in recent years has expanded the choices of clinicians for the treatment of ulcerative colitis, many patients still respond poorly to them. The remission rate during clinical induction is far from optimal. Precision and individualized treatment with traditional Chinese medicine has significant advantages in improving patient symptoms, reducing recurrence rates and adverse reactions, and improving patients’ quality of life. This article mainly introduces a case of chronic severe ulcerative colitis with significant therapeutic effect using traditional Chinese medicine combined with vedolizumab.
文章引用:宋静微, 施丽婕. 中西医结合治疗重度溃疡性结肠炎验案1则[J]. 中医学, 2024, 13(5): 895-899. https://doi.org/10.12677/tcm.2024.135136

参考文献

[1] Porter, R.J., Kalla, R. and Ho, G.-T. (2020) Ulcerative Colitis: Recent Advances in the Understanding of Disease Pathogenesis. F1000Research, 9, 294. [Google Scholar] [CrossRef] [PubMed]
[2] Le Berre, C., Honap, S. and Peyrin-Biroulet, L. (2023) Ulcerative Colitis. Lancet, 402, 571-584. [Google Scholar] [CrossRef
[3] 彭艳红. 溃疡性结肠炎中医病名源流探析[J]. 辽宁中医药大学学报, 2014, 16(3): 138-139.
[4] 张文基, 王志斌, 陈昕冉, 李军祥, 袁亚利, 邢韵淇, 王木源, 毛堂友. 基于“脾为之卫”理论探讨中医药治疗溃疡性结肠炎的免疫学策略[J]. 中国医药导报, 2023, 20(35): 50-53.
[5] 彭鑫. 《伤寒论》阳明、太阴病证与肠道微生态及人体反应性关系研究[D]: [博士学位论文]. 北京: 北京中医药大学, 2008.
[6] 纪天舒, 姜璐, 王苏童, 曹志群. 基于营卫稽留论治溃疡性结肠炎[J]. 山东中医药大学学报, 2023, 47(4): 410-413 461.
[7] 甄建华, 黄光瑞. 溃疡性结肠炎病因和发病机制的现代医学研究进展[J]. 世界华人消化杂志, 2019, 27(4): 245-251.
[8] Lu, X.Y., Jarrett, J., Sadler, S., Tan, M., Dennis, J. and Jairath, V. (2023) Comparative Efficacy of Advanced Treatments in Biologic-Naïve or Biologic-Experienced Patients with Ulcerative Colitis: A Systematic Review and Network Meta-Analysis. International Journal of Clinical Pharmacy, 45, 330-341. [Google Scholar] [CrossRef] [PubMed]
[9] 付姗姗. 共聚焦显微内镜实时检测溃疡性结肠炎粘膜微循环血流动力学的研究[D]: [硕士学位论文]. 济南: 山东大学, 2014.