关于女孩中枢性性早熟的影像学研究现状及进展
Current Status and Progress of Imaging Research on Central Precocious Puberty in Girls
DOI: 10.12677/acm.2024.1451463, PDF,    科研立项经费支持
作者: 黄雪琴, 田 露*, 蔡金华*：重庆医科大学附属儿童医院放射科，国家儿童健康与疾病临床医学研究中心，儿童发育疾病研究教育部重点实验室，儿童代谢与炎症性疾病重庆市重点实验室，重庆
关键词: 性早熟；中枢性性早熟；促性腺激素释放激素刺激试验；影像学检查；Precocious Puberty； Central Precocious Puberty； Gonadotropin-Releasing Hormone (GnRH) Stimulation Test； Imaging Examination
摘要: 中枢性早熟(CPP)是最常见的性早熟类型，指下丘脑–垂体–性腺轴(hypothalamic-pituitary-gonadal axis, HPGA)提前激活导致第二性征提前出现。临床上以促性腺激素释放激素(GnRH)刺激试验为金标准，然而该刺激实验是侵入性的、昂贵的、繁琐的。因此非侵入性的影像学检查对于CPP的诊断具有重要意义。本文综述了CPP相关影像学检查的研究现状及应用前景，包括乳腺及盆腔的超声检查、手部X线摄影的骨龄检查、头颅及垂体的磁共振检查等，旨在为CPP的影像学研究提供新思路，并为临床诊疗提供影像学依据。
Abstract: Central precocious puberty (CPP) is the most common type of precocious puberty, which refers to the early activation of the hypothalamic-pituitary-gonadal axis (HPGA), leading to the early appearance of secondary sexual characteristics. Clinically, the gonadotropin-releasing hormone (GnRH) stimulation test is usually used as the gold standard, but the test is invasive, expensive and tedious. Thus, the non-invasive imaging examination is of great significance for the diagnosis of CPP. This paper reviews the current status and prospects of CPP-related imaging examinations, including ultrasound examination of the breast and pelvis, bone age assessment through hand X-ray photography, and magnetic resonance imaging of the head and pituitary gland. The aim is to provide new insights into imaging research on CPP and to offer imaging-based evidence for clinical diagnosis and treatment.
文章引用：黄雪琴, 田露, 蔡金华. 关于女孩中枢性性早熟的影像学研究现状及进展[J]. 临床医学进展, 2024, 14(5): 559-566. https://doi.org/10.12677/acm.2024.1451463

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