睡眠障碍与高血压的研究进展
Research Progress of Sleep Disorders and Hypertension
DOI: 10.12677/acm.2024.1451490, PDF,   
作者: 庞群芳, 陈运清*:重庆医科大学附属第二医院心内科,重庆
关键词: 睡眠障碍高血压Sleep Disorders Hypertension
摘要: 近年来,睡眠障碍与高血压之间的关系备受关注。大量的研究发现,患有失眠、睡眠呼吸暂停综合症和其他睡眠障碍的个体,其患高血压的风险较正常人群明显升高。本综述总结了目前关于睡眠障碍对高血压的影响,以期为高血压患者的管理提供更全面的认识和治疗策略。
Abstract: In recent years, there has been considerable attention drawn to the relationship between sleep disorders and hypertension. A plethora of studies have revealed that individuals afflicted with insomnia, sleep apnea syndrome, and other sleep disorders experience a significantly elevated risk of hypertension compared to the general population. This review aims to consolidate the current understanding of the impact of sleep disorders on hypertension, with the intention of offering a more comprehensive insight into the management and therapeutic strategies for hypertensive patients.
文章引用:庞群芳, 陈运清. 睡眠障碍与高血压的研究进展[J]. 临床医学进展, 2024, 14(5): 773-779. https://doi.org/10.12677/acm.2024.1451490

参考文献

[1] Oparil, S., Acelajado, M.C., Bakris, G.L., Berlowitz, D.R., Cifkova, R., Dominiczak, A.F., et al. (2018) Hypertension. Nature Reviews Disease Primers, 4, Article No. 18014. [Google Scholar] [CrossRef] [PubMed]
[2] (2019) 2018 ESC Guidelines for Themanagement of Cardiovascular Diseases during Pregnancy. Revista Española de Cardiología (English Edition), 72, 161. [Google Scholar] [CrossRef] [PubMed]
[3] Lewington, S., Clarke, R., Qizilbash, N., Peto, R. and Collins, R. (2002) Age-Specific Relevance of Usual Blood Pressure to Vascular Mortality: A Meta-Analysis of Individual Data for One Million Adults in 61 Prospective Studies. The Lancet, 360, 1903-1913. [Google Scholar] [CrossRef
[4] Saiz, L.C., Gorricho, J., Garjon, J., Celaya, M.C., Erviti, J. and Leache, L. (2018) Blood Pressure Targets for the Treatment of People with Hypertension and Cardiovascular Disease. Cochrane Database of Systematic Reviews, 7, CD10315. [Google Scholar] [CrossRef
[5] Williams, B., Mancia, G., Spiering, W., Agabiti, R.E., Azizi, M., Burnier, M., et al. (2018) 2018 ESC/ESH Guidelines for the Management of Arterial Hypertension of the European Society of Cardiology (ESC) and the European Society of Hypertension (ESH). European Heart Journal, 39, 3021-3104. [Google Scholar] [CrossRef] [PubMed]
[6] Pepin, J.L., Borel, A.L., Tamisier, R., Baguet, J.P., Levy, P. and Dauvilliers, Y. (2014) Hypertension and Sleep: Overview of a Tight Relationship. Sleep Medicine Reviews, 18, 509-519. [Google Scholar] [CrossRef] [PubMed]
[7] 刘冰, 李华, 毕鸿雁. 高血压与睡眠障碍相关研究进展[J]. 中国老年保健医学, 2017, 15(3): 55-57.
[8] Thomas, S.J., Johnson, D.A., Guo, N., Abdalla, M., Booth, J.N., Spruill, T.M., et al. (2020) Association of Obstructive Sleep Apnea with Nighttime Blood Pressure in African Americans: The Jackson Heart Study. American Journal of Hypertension, 33, 949-957. [Google Scholar] [CrossRef] [PubMed]
[9] Dai, Y., Vgontzas, A.N., Chen, L., Zheng, D., Chen, B., Fernandez-Mendoza, J., et al. (2024) A Meta-Analysis of the Association between Insomnia with Objective Short Sleep Duration and Risk of Hypertension. Sleep Medicine Reviews, 75, Article 101914. [Google Scholar] [CrossRef] [PubMed]
[10] Dauvilliers, Y., Jaussent, I., Krams, B., Scholz, S., Lado, S., Levy, P., et al. (2012) Non-Dipping Blood Pressure Profile in Narcolepsy with Cataplexy. PLOS ONE, 7, e38977. [Google Scholar] [CrossRef] [PubMed]
[11] St-Onge, M.P., Grandner, M.A., Brown, D., Conroy, M.B., Jean-Louis, G., Coons, M., et al. (2016) Sleep Duration and Quality: Impact on Lifestyle Behaviors and Cardiometabolic Health: A Scientific Statement from the American Heart Association. Circulation, 134, e367-e386. [Google Scholar] [CrossRef
[12] Watson, N.F., Badr, M.S., Belenky, G., Bliwise, D.L., Buxton, O.M., Buysse, D., et al. (2015) Joint Consensus Statement of the American Academy of Sleep Medicine and Sleep Research Society on the Recommended Amount of Sleep for a Healthy Adult: Methodology and Discussion. Sleep, 38, 1161-1183. [Google Scholar] [CrossRef] [PubMed]
[13] Makarem, N., Shechter, A., Carnethon, M.R., Mullington, J.M., Hall, M.H. and Abdalla, M. (2019) Sleep Duration and Blood Pressure: Recent Advances and Future Directions. Current Hypertension Reports, 21, Article No. 33. [Google Scholar] [CrossRef] [PubMed]
[14] Gangwisch, J.E. (2014) A Review of Evidence for the Link between Sleep Duration and Hypertension. American Journal of Hypertension, 27, 1235-1242. [Google Scholar] [CrossRef] [PubMed]
[15] Gottlieb, D.J., Redline, S., Nieto, F.J., Baldwin, C.M., Newman, A.B., Resnick, H.E., et al. (2006) Association of Usual Sleep Duration with Hypertension: The Sleep Heart Health Study. Sleep, 29, 1009-1014. [Google Scholar] [CrossRef] [PubMed]
[16] Fang, J., Wheaton, A.G., Keenan, N.L., Greenlund, K.J., Perry, G.S. and Croft, J.B. (2012) Association of Sleep Duration and Hypertension among Us Adults Varies by Age and Sex. American Journal of Hypertension, 25, 335-341. [Google Scholar] [CrossRef] [PubMed]
[17] Gangwisch, J.E., Heymsfield, S.B., Boden-Albala, B., Buijs, R.M., Kreier, F., Pickering, T.G., et al. (2006) Short Sleep Duration as a Risk Factor for Hypertension: Analyses of the First National Health and Nutrition Examination Survey. Hypertension, 47, 833-839. [Google Scholar] [CrossRef
[18] Meng, L., Zheng, Y. and Hui, R. (2013) The Relationship of Sleep Duration and Insomnia to Risk of Hypertension Incidence: A Meta-Analysis of Prospective Cohort Studies. Hypertension Research, 36, 985-995. [Google Scholar] [CrossRef] [PubMed]
[19] Guo, X., Zheng, L., Wang, J., Zhang, X., Zhang, X., Li, J., et al. (2013) Epidemiological Evidence for the Link between Sleep Duration and High Blood Pressure: A Systematic Review and Meta-Analysis. Sleep Medicine, 14, 324-332. [Google Scholar] [CrossRef] [PubMed]
[20] 肖琦凡, 朱宇清. 原发性高血压患者睡眠结构与血压节律的相关性研究进展[J]. 医学综述, 2017, 23(16): 3226-3229, 3235.
[21] Legramante, J.M. and Galante, A. (2005) Sleep and Hypertension: A Challenge for the Autonomic Regulation of the Cardiovascular System. Circulation, 112, 786-788. [Google Scholar] [CrossRef
[22] 蔡珍, 艾婷婷. 睡眠时间与冠心病发病风险的研究进展[J]. 实用预防医学, 2023, 30(11): 1405-1408.
[23] Loredo, J.S., Nelesen, R., Ancoli-Israel, S. and Dimsdale, J.E. (2004) Sleep Quality and Blood Pressure Dipping in Normal Adults. Sleep, 27, 1097-1103. [Google Scholar] [CrossRef] [PubMed]
[24] Sayk, F., Teckentrup, C., Becker, C., Heutling, D., Wellhoner, P., Lehnert, H., et al. (2010) Effects of Selective Slow-Wave Sleep Deprivation on Nocturnal Blood Pressure Dipping and Daytime Blood Pressure Regulation. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 298, R191-R197. [Google Scholar] [CrossRef] [PubMed]
[25] Fung, M.M., Peters, K., Redline, S., Ziegler, M.G., Ancoli-Israel, S., Barrett-Connor, E., et al. (2011) Decreased Slow Wave Sleep Increases Risk of Developing Hypertension in Elderly Men. Hypertension, 58, 596-603. [Google Scholar] [CrossRef
[26] 程建琴, 赵丹, 张湘燕. 阻塞性睡眠呼吸暂停低通气综合征的流行病学及临床研究进展[J]. 中国呼吸与危重监护杂志, 2023, 22(12): 899-903.
[27] Zhao, X., Wang, X., Yang, T., Ji, S., Wang, H., Wang, J., et al. (2021) Classification of Sleep Apnea Based on Eeg sub-Band Signal Characteristics. Scientific Reports, 11, Article No. 5824. [Google Scholar] [CrossRef] [PubMed]
[28] Moya, E.A., Arias, P., Varela, C., Oyarce, M.P., Del, R.R. and Iturriaga, R. (2016) Intermittent Hypoxia-Induced Carotid Body Chemosensory Potentiation and Hypertension Are Critically Dependent on Peroxynitrite Formation. Oxidative Medicine and Cellular Longevity, 2016, Article ID: 9802136. [Google Scholar] [CrossRef] [PubMed]
[29] 张勰, 任洁. 阻塞性睡眠呼吸暂停低通气综合征相关高血压的研究进展[J]. 中西医结合心脑血管病杂志, 2023, 21(18): 3377-3380.
[30] Baguet, J.P., Levy, P., Barone-Rochette, G., Tamisier, R., Pierre, H., Peeters, M., et al. (2008) Masked Hypertension in Obstructive Sleep Apnea Syndrome. Journal of Hypertension, 26, 885-892. [Google Scholar] [CrossRef
[31] Macek, P., Poreba, M., Stachurska, A., Martynowicz, H., Mazur, G., Gac, P., et al. (2022) Obstructive Sleep Apnea and Sleep Structure Assessed in Polysomnography and Right Ventricular Strain Parameters. Brain Sciences, 12, Article 331. [Google Scholar] [CrossRef] [PubMed]
[32] Baguet, J.P., Boutin, I., Barone-Rochette, G., Levy, P., Tamisier, R., Pierre, H., et al. (2013) Hypertension Diagnosis in Obstructive Sleep Apnea: Self or 24-Hour Ambulatory Blood Pressure Monitoring? International Journal of Cardiology, 167, 2346-2347. [Google Scholar] [CrossRef] [PubMed]
[33] Cai, A., Wang, L. and Zhou, Y. (2016) Hypertension and Obstructive Sleep Apnea. Hypertension Research, 39, 391-395. [Google Scholar] [CrossRef] [PubMed]
[34] 孙爽, 孟亮. 失眠与高血压的研究进展[J]. 沈阳医学院学报, 2018, 20(6): 537-540.
[35] Sutton, E.L. (2021) Insomnia. Annals of Internal Medicine, 174, ITC33-ITC48. [Google Scholar] [CrossRef
[36] Ke, J., Liu, X., Ruan, X., Wu, K., Qiu, H., Wang, X., et al. (2023) Short Sleep Duration Associated with the Incidence of Cardio-Cerebral Vascular Disease: A Prospective Cohort Study in Shanghai, China. BMC Cardiovascular Disorders, 23, Article No. 177. [Google Scholar] [CrossRef] [PubMed]
[37] Vgontzas, A.N. and Chrousos, G.P. (2002) Sleep, the Hypothalamic-Pituitary-Adrenal Axis, and Cytokines: Multiple Interactions and Disturbances in Sleep Disorders. Endocrinology and Metabolism Clinics of North America, 31, 15-36. [Google Scholar] [CrossRef
[38] Zhang, Y., Elgart, M., Kurniansyah, N., Spitzer, B.W., Wang, H., Kim, D., et al. (2022) Genetic Determinants of Cardiometabolic and Pulmonary Phenotypes and Obstructive Sleep Apnoea in HCHS/SOL. eBioMedicine, 84, Article 104288. [Google Scholar] [CrossRef] [PubMed]
[39] Sejbuk, M., Mironczuk-Chodakowska, I. and Witkowska, A.M. (2022) Sleep Quality: A Narrative Review on Nutrition, Stimulants, and Physical Activity as Important Factors. Nutrients, 14, Article 1912. [Google Scholar] [CrossRef] [PubMed]
[40] Rajender, A., Mathur, S., Choudhary, P., Upadhyay, S., Rajender, G., Bhargava, R., et al. (2019) Restless Leg Syndrome a Common Undiagnosed Comorbidity of Clinical Significance in Cirrhosis. Gastroenterol Hepatol Bed Bench, 12, 13-16.
[41] Pan, W., Wang, M., Li, M., Wang, Q., Kwak, S., Jiang, W., et al. (2015) Actigraph Evaluation of Acupuncture for Treating Restless Legs Syndrome. Evidence-Based Complementary and Alternative Medicine, 2015, Article ID: 343201. [Google Scholar] [CrossRef] [PubMed]
[42] Innes, K.E., Selfe, T.K. and Agarwal, P. (2012) Restless Legs Syndrome and Conditions Associated with Metabolic Dysregulation, Sympathoadrenal Dysfunction, and Cardiovascular Disease Risk: A Systematic Review. Sleep Medicine Reviews, 16, 309-339. [Google Scholar] [CrossRef] [PubMed]
[43] Sato, M., Matsui, K., Nishimura, K. and Inoue, Y. (2024) Coexistence of Periodic Limb Movements during Sleep with Restless Legs Syndrome and Its Association with Hypertension in Japanese Patients. Sleep Medicine, 115, 187-192. [Google Scholar] [CrossRef] [PubMed]
[44] Ulfberg, J., Nystrom, B., Carter, N. and Edling, C. (2001) Prevalence of Restless Legs Syndrome among Men Aged 18 to 64 Years: An Association with Somatic Disease and Neuropsychiatric Symptoms. Movement Disorders, 16, 1159-1163. [Google Scholar] [CrossRef] [PubMed]
[45] Ohayon, M.M. and Roth, T. (2002) Prevalence of Restless Legs Syndrome and Periodic Limb Movement Disorder in the General Population. Journal of Psychosomatic Research, 53, 547-554. [Google Scholar] [CrossRef
[46] 李宗姗, 陈慧敏, 桂雅星. 发作性睡病认知障碍研究进展[J]. 中国神经免疫学和神经病学杂志, 2022, 29(3): 238-242.
[47] Thannickal, T.C., John, J., Shan, L., Swaab, D.F., Wu, M.F., Ramanathan, L., et al. (2018) Opiates Increase the Number of Hypocretin-Producing Cells in Human and Mouse Brain and Reverse Cataplexy in a Mouse Model of Narcolepsy. Science Translational Medicine, 10, eaao4953. [Google Scholar] [CrossRef] [PubMed]
[48] Grimaldi, D., Calandra-Buonaura, G., Provini, F., Agati, P., Pierangeli, G., Franceschini, C., et al. (2012) Abnormal Sleep-Cardiovascular System Interaction in Narcolepsy with Cataplexy: Effects of Hypocretin Deficiency in Humans. Sleep, 35, 519-528. [Google Scholar] [CrossRef] [PubMed]