帕金森病与前庭功能的研究进展

Advances in Vestibular Function and Parkinson’s Disease

摘要: 帕金森病(Parkinson’s Disease, PD)是一种常见的神经系统退行性疾病。因其出现运动及非运动症状，致使患者生活质量下降、生存时间缩短。目前PD无法根治，仅能通过疾病修饰延缓疾病进展，故早期诊断，早期治疗尤为重要。姿势异常和平衡障碍为PD常见的症状，已有研究表明PD患者的以上症状可能与前庭功能异常相关。目前有关前庭功能与PD的研究颇多，有研究发现PD患者早期可能出现前庭功能异常，但尚无统一定论。本文将对目前已发表的前庭功能与PD相关研究进展作进一步探讨，以期为以后的研究及临床工作提供帮助。

Abstract: Parkinson’s disease (PD) is a common neurodegenerative disease. Due to the presence of motor and non-motor symptoms, patients’ quality of life is reduced and survival time is shortened. There is currently no cure for PD, and only disease modification can slow disease progression, so early diagnosis and treatment are particularly important. Postural abnormalities and imbalance are common symptoms of PD, and it has been suggested that these symptoms in PD patients may be associated with abnormal vestibular function. At present, there are many studies on vestibular function and PD, and some studies have found that PD patients may have abnormal vestibular function in the early stages, but there is no consistent conclusion yet. In this paper, we will further discuss the progress of currently published studies related to vestibular function and PD, with the aim of contributing to further research and clinical work in the future.