骨质疏松性椎体压缩性骨折椎体成形术后骨水泥移位的研究进展
Research Progress of Bone Cement Displacement after Vertebroplasty for Osteoporotic Vertebral Compression Fracture
摘要: 经皮脊柱后凸成形术(PKP)或经皮椎体成形术(PVP)常用于临床治疗OVCF，尽管如此，仍有急性并发症以及迟发性并发症的报道。骨水泥移位作为迟发性并发症的一种，已逐渐被学者认知并进行相关研究。本文旨在通过文献综述提出这种并发症的诊断、可能原因、治疗方案以及相应的预防措施，为临床工作提供部分指导。
Abstract: Percutaneous kyphoplasty (PKP) or percutaneous vertebroplasty (PVP) is the most widely used method for the treatment of OVCF at present. However, there are still reports of acute and delayed complications. As a kind of delayed complication, bone cement displacement has been gradually recognized by scholars and related research. The purpose of this paper is to put forward the diagnosis, possible causes, treatment and corresponding preventive measures of this complication through literature review, so as to provide some guidance for clinical work.
文章引用：周文逸, 赵郭盛, 汪洋, 柯珍勇. 骨质疏松性椎体压缩性骨折椎体成形术后骨水泥移位的研究进展[J]. 临床医学进展, 2024, 14(5): 2103-2110. https://doi.org/10.12677/acm.2024.1451656

参考文献

[1] Parreira, P., Maher, C.G., Megale, R.Z., et al. (2017) An Overview of Clinical Guidelines for the Management of Vertebral Compression Fracture: A Systematic Review. The Spine Journal, 17, 1932-1938. [Google Scholar] [CrossRef] [PubMed]
[2] Li, Y., Feng, X., Pan, J., et al. (2021) Percutaneous Vertebroplasty versus Kyphoplasty for Thoracolumbar Osteoporotic Vertebral Compression Fractures in Patients with Distant Lumbosacral Pain. Pain Physician, 24, E349-E356. [Google Scholar] [CrossRef] 
[3] Cao, Z., Wang, G., Hui, W., et al. (2020) Percutaneous Kyphoplasty for Osteoporotic Vertebral Compression Fractures Improves Spino-Pelvic Alignment and Global Sagittal Balance Maximally in the Thoracolumbar Region. PLOS ONE, 15, e228341. [Google Scholar] [CrossRef] [PubMed]
[4] Zhang, Y., Zhang, T., Ge, X., et al. (2022) A Three-Dimensional Cement Quantification Method for Decision Prediction of Vertebral Recompression after Vertebroplasty. Computational and Mathematical Methods in Medicine, 2022, Article ID: 2330472. [Google Scholar] [CrossRef] [PubMed]
[5] Zhong, S., Bao, F., Fan, Q., et al. (2023) Prevention of Bone Cement Displacement in Kümmell Disease without Neurological Deficits through Treatment with a Novel Hollow Pedicle Screw Combined with Kyphoplasty. Orthopaedic Surgery, 15, 2515-2522. [Google Scholar] [CrossRef] [PubMed]
[6] Qi, J., Hu, Y., Yang, Z., et al. (2022) Incidence, Risk Factors, and Outcomes of Symptomatic Bone Cement Displacement Following Percutaneous Kyphoplasty for Osteoporotic Vertebral Compression Fracture: A Single Center Study. Journal of Clinical Medicine, 11, Article 7530. [Google Scholar] [CrossRef] [PubMed]
[7] Gao, X., Du, J., Gao, L., et al. (2022) Risk Factors for Bone Cement Displacement after Percutaneous Vertebral Augmentation for Osteoporotic Vertebral Compression Fractures. Frontiers in Surgery, 9, Article 947212. [Google Scholar] [CrossRef] [PubMed]
[8] Gao, X., Du, J., Zhang, Y., et al. (2022) Predictive Factors for Bone Cement Displacement Following Percutaneous Vertebral Augmentation in Kümmell’s Disease. Journal of Clinical Medicine, 11, Article 7479. [Google Scholar] [CrossRef] [PubMed]
[9] Yu, W., Jiang, X., Liang, D., et al. (2017) Intravertebral Vacuum Cleft and Its Varied Locations within Osteoporotic Vertebral Compression Fractures: Effect on Therapeutic Efficacy. Pain Physician, 20, E979-E986. [Google Scholar] [CrossRef] 
[10] Prakash Prabhu, L.V., Saralaya, V.V., et al. (2007) Vertebral Body Integrity: A Review of Various Anatomical Factors Involved in the Lumbar Region. Osteoporosis International, 18, 891-903. [Google Scholar] [CrossRef] [PubMed]
[11] Ratcliffe, J.F. (1980) The Arterial Anatomy of the Adult Human Lumbar Vertebral Body: A Microarteriographic Study. Journal of Anatomy, 131, 57-79.
[12] Ding, J., Zhang, Q., Zhu, J., et al. (2016) Risk Factors for Predicting Cement Leakage Following Percutaneous Vertebroplasty for Osteoporotic Vertebral Compression Fractures. European Spine Journal, 25, 3411-3417. [Google Scholar] [CrossRef] [PubMed]
[13] Nagad, P., Rawall, S., Kundnani, V., et al. (2012) Postvertebroplasty Instability. Journal of Neurosurgery: Spine, 16, 387-393. [Google Scholar] [CrossRef] 
[14] Nakano, M., Hirano, N., Ishihara, H., et al. (2005) Calcium Phosphate Cement Leakage after Percutaneous Vertebroplasty for Osteoporotic Vertebral Fractures: Risk Factor Analysis for Cement Leakage. Journal of Neurosurgery: Spine, 2, 27-33. [Google Scholar] [CrossRef] [PubMed]
[15] Mo, L., Wu, Z., Liang, D., et al. (2021) Influence of Bone Cement Distribution on Outcomes Following Percutaneous Vertebroplasty: A Retrospective Matched-Cohort Study. Journal of International Medical Research, 49, Article No. 03000605211022287. [Google Scholar] [CrossRef] [PubMed]
[16] Zhang, J., Fan, Y., He, X., et al. (2019) Bracing after Percutaneous Vertebroplasty for Thoracolumbar Osteoporotic Vertebral Compression Fractures Was Not Effective. Clinical Interventions in Aging, 14, 265-270. [Google Scholar] [CrossRef] 
[17] Heo, D.H., Chin, D.K., Yoon, Y.S., et al. (2009) Recollapse of Previous Vertebral Compression Fracture after Percutaneous Vertebroplasty. Osteoporosis International, 20, 473-480. [Google Scholar] [CrossRef] [PubMed]
[18] Lavelle, W.F., Cheney, R. (2006) Recurrent Fracture after Vertebral Kyphoplasty. Spine Journal, 6, 488-493. [Google Scholar] [CrossRef] [PubMed]
[19] Liu, Y., Dash, A., Krez, A., et al. (2020) Low Volumetric Bone Density Is a Risk Factor for Early Complications after Spine Fusion Surgery. Osteoporosis International, 31, 647-654. [Google Scholar] [CrossRef] [PubMed]
[20] Svejme, O., Ahlborg, H.G., Nilsson, J.Å., et al. (2013) Low BMD Is an Independent Predictor of Fracture and Early Menopause of Mortality in Post-Menopausal Women—A 34-Year Prospective Study. Maturitas, 74, 341-345. [Google Scholar] [CrossRef] [PubMed]
[21] Arceo-Mendoza, R.M. and Camacho, P.M. (2021) Postmenopausal Osteoporosis: Latest Guidelines. Endocrinology and Metabolism Clinics of North America, 50, 167-178. [Google Scholar] [CrossRef] [PubMed]
[22] Chiu, Y.C., Yang, S.C., Chen, H.S., et al. (2015) Posterior Transpedicular Approach with Circumferential Debridement and Anterior Reconstruction as a Salvage Procedure for Symptomatic Failed Vertebroplasty. Journal of Orthopaedic Surgery and Research, 10, Article No. 28. [Google Scholar] [CrossRef] [PubMed]
[23] Ha, K.Y., Kim, K.W., Kim, Y.H., et al. (2010) Revision Surgery after Vertebroplasty or Kyphoplasty. Clinics in Orthopedic Surgery, 2, 203-208. [Google Scholar] [CrossRef] [PubMed]
[24] Ha, K.Y., Kim, Y.H., Yoo, S.R., et al. (2015) Bone Cement Dislodgement: One of Complications Following Bone Cement Augmentation Procedures for Osteoporotic Spinal Fracture. Journal of Korean Neurosurgical Society, 57, 367-370. [Google Scholar] [CrossRef] [PubMed]
[25] Huang, A., Fang, S., Wang, L., et al. (2019) Vertebral Collapse and Polymethylmethacrylate Breakage after Vertebroplasty: A Case Report. Medicine, 98, e16831. [Google Scholar] [CrossRef] 
[26] Jeong, Y.H., Lee, C.J., Yeon, J.T., et al. (2016) Insufficient Penetration of Bone Cement into the Trabecular Bone: A Potential Risk for Delayed Bone Cement Displacement after Kyphoplasty? Regional Anesthesia & Pain Medicine, 41, 616-618. [Google Scholar] [CrossRef] 
[27] Kim, J.E., Choi, S.S., Lee, M.K., et al. (2017) Failed Percutaneous Vertebroplasty Due to Insufficient Correction of Intravertebral Instability in Kummell’s Disease: A Case Report. Pain Practice, 17, 1109-1114. [Google Scholar] [CrossRef] [PubMed]
[28] Mueller, M., Daniels-Wredenhagen, M., Besch, L., et al. (2009) Postoperative Aseptic Osteonecrosis in a Case of Kyphoplasty. European Spine Journal, 18, 213-216. [Google Scholar] [CrossRef] [PubMed]
[29] Nüchterlein, M. and Bail, H.J. (2013) [A Rare Complication of Kyphoplasty Is PMMA-Cement Loosening—Case Report and Literature Review]. Zeitschrift für Orthopädie und Unfallchirurgie, 151, 463-467. [Google Scholar] [CrossRef] [PubMed]
[30] Tsai, T.T., Chen, W.J., Lai, P.L., et al. (2003) Polymethylmethacrylate Cement Dislodgment Following Percutaneous Vertebroplasty: A Case Report. Spine, 28, E457-E460. [Google Scholar] [CrossRef] 
[31] Wagner, A.L. and Baskurt, E. (2006) Refracture with Cement Extrusion Following Percutaneous Vertebroplasty of a Large Interbody Cleft. American Journal of Neuroradiology, 27, 230-231.
[32] Wang, H.S., Kim, H.S., Ju, C.I., et al. (2008) Delayed Bone Cement Displacement Following Balloon Kyphoplasty. Journal of Korean Neurosurgical Society, 43, 212-214. [Google Scholar] [CrossRef] [PubMed]
[33] Yang, S.C., Chen, W.J., Yu, S.W., et al. (2008) Revision Strategies for Complications and Failure of Vertebroplasties. European Spine Journal, 17, 982-988. [Google Scholar] [CrossRef] [PubMed]
[34] Yoshii, T., Ueki, H., Kato, T., et al. (2014) Severe Kyphotic Deformity Resulting From Collapses of Cemented and Adjacent Vertebrae Following Percutaneous Vertebroplasty Using Calcium Phosphate Cement. A Case Report. Skeletal Radiology, 43, 1477-1480. [Google Scholar] [CrossRef] [PubMed]
[35] Zhang, C., Wang, G., Liu, X., et al. (2017) Failed Percutaneous Kyphoplasty in Treatment of Stage 3 Kummell Disease: A Case Report and Literature Review. Medicine, 96, e8895. [Google Scholar] [CrossRef] 
[36] Ha, K.Y., Kim, Y.H., Chang, D.G., et al. (2013) Causes of Late Revision Surgery after Bone Cement Augmentation in Osteoporotic Vertebral Compression Fractures. Asian Spine Journal, 7, 294-300. [Google Scholar] [CrossRef] [PubMed]
[37] Wang, B., Wang, Y., Zhang, H., et al. (2021) A Novel Bone Cement Screw System Combined with Vertebroplasty for the Treatment of Kummell Disease with Bone Deficiency at the Vertebral Anterior Border: A Minimum 3-Year Follow-Up Study. Clinical Neurology and Neurosurgery, 201, Article ID: 106434. [Google Scholar] [CrossRef] [PubMed]
[38] Wang, B., Zhan, Y., Bai, Y., et al. (2022) Biomechanical Analysis of a Novel Bone Cement Bridging Screw System for the Treatment of Kummell Disease: A Finite Element Analysis. American Journal of Translational Research, 14, 7052-7062.
[39] Zhong, C., Min, G., Liu, X.W., et al. (2021) Percutaneous Vertebroplasty Using a Rotary Cutter for Treating Kümmell’s Disease with Intravertebral Vacuum Cleft. Pain Physician, 24, E477-E482. [Google Scholar] [CrossRef] 
[40] Wang, B., Wang, Y., Zhao, Q., et al. (2020) Pediculoplasty Combined with Vertebroplasty for the Treatment of Kummell’s Disease without Neurological Impairment: Robot-Assisted and Fluoroscopy-Guided. American Journal of Translational Research, 12, 8019-8029.
[41] Dai, S., Du, Y., Chen, L., et al. (2023) A Mid-and Long-Term Follow-Up Study on the Bilateral Pedicle Anchoring Technique with Percutaneous Vertebroplasty for the Treatment of Kümmell’s Disease. Frontiers in Surgery, 10, Article 1061498. [Google Scholar] [CrossRef] [PubMed]
[42] 高鼎智, 石磊, 晏铮剑, 等. 经皮椎弓根骨水泥螺钉锚定结合椎体成形术治疗Kümmell病的疗效探讨[J]. 重庆医学, 2023, 52(22): 3413-3418, 3424.
[43] 姚汝斌, 王仕永, 杨开舜. 椎弓根内骨水泥灌注联合椎体后凸成形治疗Kummell病: 增强椎体内骨水泥团块稳定性[J]. 中国组织工程研究, 2021, 25(28): 4435-4440.
[44] 李红桃, 潘泓宇, 雷杨, 等. 经皮椎体成形联合椎弓根强化治疗重度骨质疏松性椎体骨折: 有限元分析[J/OL]. 中国组织工程研究, 2024: 1-6.

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