正念认知疗法在复发性抑郁中的应用研究
Research on the Application of Mindfulness-Based Cognitive Therapy in Recurrent Depression
摘要: 本研究针对复发性抑郁症患者，深度梳理了国内外关于正念认知疗法(MBCT)的最新进展。现有证据证实，正念认知疗法在防止抑郁症复发方面展现出了良好的疗效。考虑到抑郁症治疗情境的多样性和复杂性，目前业界尚未形成一套普遍适用的标准治疗程序，构建并验证标准化的正念认知疗法在复发性抑郁症治疗中的具体操作流程，将是未来研究亟待解决和深化探索的关键议题。
Abstract: This study is aimed at patients with recurrent depression, and the latest progress of the positive cognitive therapy (MBCT) is deeply reviewed. Existing evidence confirms that mindfulness cognitive therapy has shown good results in preventing the recurrence of depression. Considering the diversity and complexity of the treatment situation of depression, the present industry has not yet formed a universal standard treatment program, and the concrete operation process of the standardized mindfulness cognitive therapy in the treatment of recurrent depression is a key issue in future research to solve and deepen the exploration.
文章引用：高鑫智, 葛波, 杨奇伟 (2024). 正念认知疗法在复发性抑郁中的应用研究. 心理学进展, 14(5), 394-402. https://doi.org/10.12677/ap.2024.145326

参考文献

[1] 冯春娣, 薄伟, 杨琴(2023). 正念认知疗法对抑郁症患者的影响分析. 心理月刊, 18(9), 111-113, 116.
[2] 李丹(2015). 抑郁症患者反应抑制和情绪冲突的ERP及fMRI研究. 硕士学位论文, 重庆: 重庆医科大学.
[3] 李娟, 罗香群, 王婧(2022). 正念认知疗法对大学生抑郁情绪的干预研究. 心理月刊, (15), 18-20, 24.
[4] 孙继飞, 马跃, 郭春蕾, 等(2022). 复发性与首发性抑郁症杏仁核静息态功能连接的对比研究. 磁共振成像, 13(10), 144-149.
[5] 王欣, 坦力甫江∙买买提(2022). 正念认知疗法联合药物对抑郁症患者残留症状疗效及生活质量影响. 中国现代医生, 60(17), 128-131, 139.
[6] 邢敏智(2021). 反刍思维在认知功能和抑郁症状间的中介效应. 硕士学位论文, 温州: 温州医科大学.
[7] Aalderen, J. R., van Donders, A. R. T., Giommi, F., Spinhoven, P., Barendregt, H. P., & Speckens, A. E. M. (2012). The Efficacy of Mindfulness-Based Cognitive Therapy in Recurrent Depressed Patients with and without a Current Depressive Episode: A Randomized Controlled Trial. Psychological Medicine, 42, 989-1001. http://hdl.handle.net/2066/109819[CrossRef] 
[8] Ames, C. S., Richardson, J., Payne, S., Smith, P., & Leigh, E. (2014). Mindfulness-Based Cognitive Therapy for Depression in Adolescents. Child and Adolescent Mental Health, 19, 74-78.[CrossRef] [PubMed]
[9] Avest, M. J. ter, Greven, C. U., Huijbers, M. J., Wilderjans, T. F., Speckens, A. E. M., & Spinhoven, P. (2020). Prospective Associations between Home Practice and Depressive Symptoms in Mindfulness-Based Cognitive Therapy for Recurrent Depression: A 15 Months Follow-Up Study. Cognitive Therapy and Research, 45, 250-261.
https://hdl.handle.net/1887/3184561
[10] Banov, M. (2018). Management of Depression, Part 2: Treatment Options. Decker Med Psychiatry.
[11] Belliveau, C., Nagy, C., Escobar, S., Mechawar, N., Turecki, G., Rej, S., & Torres-Platas, S. G. (2021). Effects of Mindfulness-Based Cognitive Therapy on Peripheral Markers of Stress and Inflammation in Older-Adults with Depression and Anxiety: A Parallel Analysis of a Randomized Controlled Trial. Frontiers in Psychiatry, 12, Article 804269.[CrossRef] [PubMed]
[12] Bondolfi, G., Jermann, F., der Linden, M. V., Gex-Fabry, M., Bizzini, L., Rouget, B. W., Myers-Arrazola, L., Gonzalez, C., Segal, Z., Aubry, J. M., & Bertschy, G. (2010). Depression Relapse Prophylaxis with Mindfulness-Based Cognitive Therapy: Replication and Extension in the Swiss Health Care System. Journal of Affective Disorders, 122, 224-231.[CrossRef] [PubMed]
[13] Chiesa, A., Castagner, V., Andrisano, C., Serretti, A., Mandelli, L., Porcelli, S., & Giommi, F. (2015). Mindfulness-Based Cognitive Therapy vs. Psycho-Education for Patients with Major Depression Who Did Not Achieve Remission Following Antidepressant Treatment. Psychiatry Research, 226, 474-483.[CrossRef] [PubMed]
[14] Cladder-Micus, M. B., Vrijsen, J. N., Becker, E. S., Donders, R., Spijker, J., & Speckens, A. E. (2015). A Randomized Controlled Trial of Mindfulness-Based Cognitive Therapy (MBCT) versus Treatment-As-Usual (TAU) for Chronic, Treatment-Resistant Depression: Study Protocol. BMC Psychiatry, 15, Article No. 275.[CrossRef] [PubMed]
[15] De Klerk-Sluis, J. M., Huijbers, M. J., Löcke, S., Spijker, J., Spinhoven, P., Speckens, A. E., & Ruhe, H. G. (2022). Factors Associated with Relapse and Recurrence of Major Depressive Disorder in Patients Starting Mindfulness-Based Cognitive Therapy. Depression and Anxiety, 39, 113-122.[CrossRef] [PubMed]
[16] De Raedt, R., Baert, S., Demeyer, I., Goeleven, E., Raes, A., Visser, A., Wysmans, M., Jansen, E., Schacht, R., Van Aalderen, J. R., & Speckens, A. (2012). Changes in Attentional Processing of Emotional Information Following Mindfulness-Based Cognitive Therapy in People with a History of Depression: Towards an Open Attention for All Emotional Experiences. Cognitive Therapy and Research, 36, 612-620.
https://biblio.ugent.be/publication/2958432
[17] Dikaios, E., Escobar, S., Nassim, M., Su, C. L., Torres-Platas, S. G., & Rej, S. (2020). Continuation Sessions of Mindfulness-Based Cognitive Therapy (MBCT-C) vs. Treatment as Usual in Late-Life Depression and Anxiety: An Open-Label Extension Study. International Journal of Geriatric Psychiatry, 35, 1228-1232.[CrossRef] [PubMed]
[18] Dwyer, J. B., Landeros-Weisenberger, A., Johnson, J. A., Londono Tobon, A., Flores, J. M., Nasir, M. et al. (2022). Efficacy of Intravenous Ketamine in Adolescent Treatment-Resistant Depression: A Randomized Midazolam-Controlled Trial. American Journal of Psychiatry, 178, 352-362.[CrossRef] [PubMed]
[19] Finucane, A., & Mercer, S. W. (2006). An Exploratory Mixed Methods Study of the Acceptability and Effectiveness of Mindfulness-Based Cognitive Therapy for Patients with Active Depression and Anxiety in Primary Care. BMC Psychiatry, 6, Article No. 14. http://www.biomedcentral.com/1471-244X/6/14[CrossRef] 
[20] Foroughi, A., Sadeghi, K., Parvizifard, A., Parsa Moghadam, A., Davarinejad, O., Farnia, V., & Azar, G. (2020). The Effectiveness of Mindfulness-Based Cognitive Therapy for Reducing Rumination and Improving Mindfulness and Self-Compassion in Patients with Treatment-Resistant Depression. Trends in Psychiatry and Psychotherapy, 42, 138-146.[CrossRef] [PubMed]
[21] Frostadottir, A. D., & Dorjee, D. (2019). Effects of Mindfulness Based Cognitive Therapy (MBCT) and Compassion Focused Therapy (CFT) on Symptom Change, Mindfulness, Self-Compassion, and Rumination in Clients with Depression, Anxiety, and Stress. Frontiers in Psychology, 10, Article 422491.[CrossRef] [PubMed]
[22] Gex-Fabry, M., Jermann, F., Kosel, M., Rossier, M. F., Van der Linden, M., Bertschy, G., Bondolfi, G., & Aubry, J. M. (2012). Salivary Cortisol Profiles in Patients Remitted from Recurrent Depression: One-Year Follow-Up of a Mindfulness-Based Cognitive Therapy Trial. Journal of Psychiatric Research, 46, 80-86.[CrossRef] [PubMed]
[23] Goodman, S. H., & Gotlib, I. H. (1999). Risk for Psychopathology in the Children of Depressed Mothers: A Developmental Model for Understanding Mechanisms of Transmission. Psychological Review, 106, 458-490.[CrossRef] 
[24] Gu, S. M., Li, Y. W., Liang, F., Feng, R., Zeng, Z., & Wang, F. S. (2020). The Mediating Effects of Coping Style on the Effects of Breath Count Mindfulness Training on Depressive Symptoms among International Students in China. Neural Plasticity, 2020, Article ID: 8859251.[CrossRef] [PubMed]
[25] Guan, C., Wen, X., Gong, Y., Liang, Y., & Wang, Z. (2013). Family Environment and Depression: A Population-Based Analysis of Gender Differences in Rural China. Journal of Family Issues, 35, 481-500.[CrossRef] 
[26] Jin, J., Tang, Y. Y., Ma, Y., Lv, S., Bai, Y., & Zhang, H. (2009). A Structural Equation Model of Depression and the Defense System Factors: A Survey among Chinese College Students. Psychiatry Research, 165, 288-296.[CrossRef] [PubMed]
[27] Kane, P., & Garber, J. (2009). Parental Depression and Child Externalizing and Internalizing Symptoms: Unique Effects of Fathers’ Symptoms and Perceived Conflict as a Mediator. Journal of Child and Family Studies, 18, 465-472.[CrossRef] 
[28] Kessler, R. C., & Bromet, E. J. (2013). The Epidemiology of Depression across Cultures. Annual Review of Public Health, 34, 119-138.[CrossRef] [PubMed]
[29] Kingston, T., Dooley, B., Bates, A., Lawlor, E., & Malone, K. (2007). Mindfulness-Based Cognitive Therapy for Residual Depressive Symptoms. Psychology and Psychotherapy: Theory, Research and Practice, 80, 193-203.[CrossRef] 
[30] Kuyken, W., Byford, S., Byng, R., Dalgleish, T., Lewis, G., Taylor, R. et al. (2010). Study Protocol for a Randomized Controlled Trial Comparing Mindfulness-Based Cognitive Therapy with Maintenance Anti-Depressant Treatment in the Prevention of Depressive Relapse/Recurrence: The PREVENT Trial. Trials, 11, Article No. 99.[CrossRef] [PubMed]
[31] Kuyken, W., Crane, R., & Dalgleish, T. (2012). Does Mindfulness Based Cognitive Therapy Prevent Relapse of Depression? BMJ, 345, e7194.[CrossRef] [PubMed]
[32] Kuyken, W., Hayes, R., Barrett, B., Byng, R., Dalgleish, T., Kessler, D. et al. (2015). Effectiveness and Cost-Effectiveness of Mindfulness-Based Cognitive Therapy Compared with Maintenance Antidepressant Treatment in the Prevention of Depressive Relapse or Recurrence (PREVENT): A Randomised Controlled Trial. The Lancet, 386, 63-73.[CrossRef] 
[33] Kuyken, W., Warren, F. C., Taylor, R. S., Whalley, B., Crane, C., Bondolfi, G., Hayes, R., Huijbers, M., Ma, H., Schweizer, S., Segal, Z., Speckens, A., Teasdale, J. D., Van Heeringen, K., Williams, M., Byford, S., Byng, R., & Dalgleish, T. (2016). Efficacy of Mindfulness-Based Cognitive Therapy in Prevention of Depressive Relapse an Individual Patient Data Meta-Analysis from Randomized Trials. JAMA Psychiatry, 73, 565-574.[CrossRef] [PubMed]
[34] Li, H., Yan, W., Wang, Q., Liu, L., Lin, X., Zhu, X. et al. (2022). Mindfulness-Based Cognitive Therapy Regulates Brain Connectivity in Patients with Late-Life Depression. Frontiers in Psychiatry, 13, Article 841461.[CrossRef] [PubMed]
[35] Lomas, T., Ivtzan, I., & Fu, C. H. (2015). A Systematic Review of the Neurophysiology of Mindfulness on EEG Oscillations. Neuroscience & Biobehavioral Reviews, 57, 401-410.[CrossRef] [PubMed]
[36] Mann, J., Kuyken, W., O’Mahen, H., Ukoumunne, O. C., Evans, A., & Ford, T. (2016). Manual Development and Pilot Randomised Controlled Trial of Mindfulness-Based Cognitive Therapy versus Usual Care for Parents with a History of Depression. Mindfulness, 7, 1024-1033.[CrossRef] [PubMed]
[37] Mars, B., Collishaw, S., Smith, D., Thapar, A., Potter, R., Sellers, R. et al. (2012). Offspring of Parents with Recurrent Depression: Which Features of Parent Depression Index Risk for Offspring Psychopathology? Journal of Affective Disorders, 136, 44-53.[CrossRef] [PubMed]
[38] Michalak, J., Hölz, A., & Teismann, T. (2011). Rumination as a Predictor of Relapse in Mindfulness-Based Cognitive Therapy for Depression. Psychology and Psychotherapy: Theory, Research and Practice, 84, 230-236.[CrossRef] 
[39] Murphy, H., & Lahtinen, M. (2011). Understanding the Impact of Meditative Homeworkon Depression in the Context of Mindfulness Based Cognitive Therapy (MBCT): An Interpretative Phenomenological Analysis. European Psychiatry, 26, 659.[CrossRef] 
[40] Probst, T., Schramm, E., Heidenreich, T., Klein, J. P., & Michalak, J. (2020). Patients’ Interpersonal Problems as Moderators of Depression Outcomes in a Randomized Controlled Trial Comparing Mindfulness-Based Cognitive Therapy and a Group Version of the Cognitive-Behavioral Analysis System of Psychotherapy in Chronic Depression. Journal of Clinical Psychology, 76, 1241-1254.[CrossRef] [PubMed]
[41] Raes, F., Dewulf, D., Van Heeringen, C., & Williams, J. M. G. (2009). Mindfulness and Reduced Cognitive Reactivity to Sad Mood: Evidence from a Correlational Study and a Non-Randomized Waiting List Controlled Study. Behaviour Research and Therapy, 47, 623-627.[CrossRef] [PubMed]
[42] Restifo, K., & Bögels, S. (2009). Family Processes in the Development of Youth Depression: Translating the Evidence to Treatment. Clinical Psychology Review, 29, 294-316.[CrossRef] [PubMed]
[43] Segal, Z., Williams, M., & Teasdale, J. (2018). Mindfulness-Based Cognitive Therapy for Depression. Guilford Publications.
[44] Smith, A., Graham, L., & Senthinathan, S. (2023). Mindfulness-Based Cognitive Therapy for Recurring Depression in Older People: A Qualitative Study. Aging and Mental Health, 11, 346-357.[CrossRef] [PubMed]
[45] Snippe, E., Nyklíček, I., Schroevers, M. J., & Bos, E. H. (2017). The Temporal Order of Change in Daily Mindfulness and Affect during Mindfulness-Based Stress Reduction. Journal of Counseling Psychology, 62, 106-114.[CrossRef] [PubMed]
[46] Tang, Y. Y., Tang, R., Rothbart, M. K., & Posner, M. I. (2019). Frontal Theta Activity and White Matter Plasticity Following Mindfulness Meditation. Current Opinion in Psychology, 28, 294-297.[CrossRef] [PubMed]
[47] Tickell, A., Byng, R., Crane, C., Gradinger, F., Hayes, R., Robson, J. et al. (2020). Recovery from Recurrent Depression with Mindfulness-Based Cognitive Therapy and Antidepressants: A Qualitative Study with Illustrative Case Studies. BMJ Open, 10, e033892.[CrossRef] [PubMed]
[48] Velden, A. M., Piet, J., Møller, A. B., & Fjorback, L. (2017). Mindfulness-Based Cognitive Therapy Is Efficient in the Treatment of Recurrent Depression. Ugeskrift for Laeger, 179, v04160291.
[49] Williams, J. M., Crane, C., Barnhofer, T., Brennan, K., Duggan, D., Fennell, M., Hackmann, A., Krusche, A., Muse, K., von Rohr, I. R., Shah, D., Crane, R. S., Eames, C., Jones, M., Radford, S., Silverton, S., Sun, Y., Weatherley-Jones, E., Whi-taker, C., Russell, I. et al. (2014). Mindfulness-Based Cognitive Therapy for Preventing Relapse in Recurrent Depression: A Randomized Dismantling Trial. Journal of Consulting and Clinical Psychology, 82, 275-286.
https://eprints.glos.ac.uk/11004/
[50] Wood, L. C. (2011). Mindfulness-Based Cognitive Therapy for Recurrent Depression and Anxiety.[CrossRef] 
[51] World Health Organization (2012). Depression Fact Sheet No. 369.
[52] Yan, Y., Zhang, J., & Dong, S. (2021). Influence of Childhood Family Routines on Adult Depression: A Cross Sectional Study. Frontiers in Psychology, 12, Article 654433.[CrossRef] [PubMed]
[53] Yee, N. Y., & Sulaiman, W. S. W. (2017). Resilience as Mediator in the Relationship between Family Functioning and Depression among Adolescents from Single Parent Families. Akademika, 87, 111-122.[CrossRef]