强迫症的心理机制及数字化疗法
Psychological Mechanism and Digital Therapy of Obsessive-Compulsive Disorder
摘要: 强迫症是一种严重且致残的精神疾病,对心理学和神经科学等领域提出了诸多挑战。其在世界范围的终生患病率为1%~2.3%,是精神分裂症的两倍,且它的病程通常是长期的。同时,强迫症是一种潜在的失能性精神疾病,约30%的患者对常规治疗的结果反应并不理想。其发病机制作为疗法的基础仍在不断更新,其动态化发展不断为新疗法带来福祉。近来不少研究利用信息技术进行联合治疗,发现能够有效改善强迫症状。未来应从联合视角考虑结合数字化技术设计个人化的强迫症治疗方案,以最大化发挥药物和心理治疗的效果;同时通过数字化背景增强大众对强迫症的识别能力和筛查意识。
Abstract: Obsessive-compulsive disorder (OCD) is a serious and disabling mental illness that presents numerous challenges to fields such as psychology and neuroscience. Its lifetime prevalence worldwide is 1%~2.3%, is twice as common as schizophrenia, and its course is usually long-term. At the same time, OCD is a potentially disabling mental disorder, with about 30% of patients not responding well to the results of conventional treatment. Its pathogenesis is still being updated as the basis of therapy, and its dynamic development continues to bring benefits to new therapies. A number of recent studies using information technology for combination therapy have found that it can effectively improve compulsive symptoms. In the future, we should consider the combination of digital technology to design personalized OCD treatment plan, in order to maximize the effect of drug and psychological treatment; At the same time, through the digital background to enhance the public's ability to identify OCD and screening awareness
文章引用:许钰羚 (2024). 强迫症的心理机制及数字化疗法. 心理学进展, 14(5), 403-414. https://doi.org/10.12677/ap.2024.145327

参考文献

[1] 保宏翔(2021). 强迫症高危人群人格量表编制与CAT化及其眼动特征研究. 博士学位论文, 西安: 中国人民解放军空军军医大学.[CrossRef
[2] 蒋成娣, 乔兴菊, 路多(2022). 认知行为疗法在强迫症患者中的应用价值. 河南医学研究, 31(6), 1082-1085.
[3] 田丽, 胡纪泽(2013). 强迫症的认知理论. 中国健康心理学杂志, 21(7), 1120-1121.[CrossRef
[4] 杨晓沙(2019). 正念认知疗法在强迫症治疗中的研究现状. 硕士学位论文, 重庆: 重庆医科大学.
https://kns.cnki.net/kcms2/article/abstract?v=3uoqIhG8C475KOm_zrgu4lQARvep2SAkEcTGK3Qt5VuzQzk0e7M1zzq25YfaRfUA7wV5zGFH1kLn24W8hNgMtybDyWemt8Dk&uniplatform=NZKPT
[5] 朱佳, 黄宁宁, 吴恩辉(2023). 虚拟现实技术联合虚拟场景暴露反应/仪式阻断治疗技术对女性强迫症患者治疗依从性的影响. 中国妇幼保健, 38(11), 2101-2104.[CrossRef
[6] 邹苏(2022). 地方综合性大学学生心理疾病观研究. 校园心理, 20(5), 335-341.[CrossRef
[7] Banca, P., Voon, V., Vestergaard, M. D., Philipiak, G., Almeida, I., Pocinho, F., Relvas, J., & Castelo-Branco, M. (2015). Imbalance in Habitual versus Goal Directed Neural Systems during Symptom Provocation in Obsessive-Compulsive Disorder. Brain, 138, 798-811.[CrossRef] [PubMed]
[8] Baus, O., & Bouchard, S. (2014). Moving from Virtual Reality Exposure-Based Therapy to Augmented Reality Exposure-Based Therapy: A Review. Frontiers in Human Neuroscience, 8, Article No. 112.[CrossRef] [PubMed]
[9] Bey, K., Weinhold, L., Gruetzmann, R., Heinzel, S., Kaufmann, C., Klawohn, J., Riesel, A., Lennertz, L., Schmid, M., Ramirez, A., Kathmann, N., & Wagner, M. (2020). The Polygenic Risk for Obsessive-Compulsive Disorder Is Associated with the Personality Trait Harm Avoidance. Acta Psychiatrica Scandinavica, 142, 326-336.[CrossRef] [PubMed]
[10] Blanco-Vieira, T., Hoexter, M. Q., Batistuzzo, M. C., Alvarenga, P., Szejko, N., Fumo, A. M. T., Miguel, E. C., & Do Rosário, M. C. (2021). Association between Obsessive-Compulsive Symptom Dimensions in Mothers and Psychopathology in Their Children. Frontiers in Psychiatry, 12, Article ID: 674261.[CrossRef] [PubMed]
[11] Blanco-Vieira, T., Radua, J., Marcelino, L., Bloch, M., Mataix-Cols, D., & Do Rosário, M. C. (2023). The Genetic Epidemiology of Obsessive-Compulsive Disorder: A Systematic Review and Meta-Analysis. Translational Psychiatry, 13, Article No. 230.[CrossRef] [PubMed]
[12] Cervin, M., & Perrin, S. (2021). Incompleteness and Disgust Predict Treatment Outcome in Pediatric Obsessive-Compulsive Disorder. Behavior Therapy, 52, 53-63.[CrossRef] [PubMed]
[13] Chai, X., Tian, Y., Gong, S., & Liu, Y. (2014). A Metacognition Approach to Characteristics of Obsessive-Compulsive Disorder, Model and Intervention. Advances in Psychological Science, 22, 97-103.[CrossRef
[14] Department of Psichiatry, Firat University School of Medicine, Elazig, Turkey, & Atmaca, M. (2022). Metacognitive Therapy in Patients with Obsessive Compulsive Disorder: A Review. Alpha Psychiatry, 23, 212-216.[CrossRef] [PubMed]
[15] Duan, L. Y., Horst, N. K., Cranmore, S. A. W., Horiguchi, N., Cardinal, R. N., Roberts, A. C., & Robbins, T. W. (2021). Controlling One’s World: Identification of Sub-Regions of Primate PFC Underlying Goal-Directed Behavior. Neuron, 109, 2485-2498.e5.[CrossRef] [PubMed]
[16] Fajnerova, I., Francova, A., Taranzova, K., Darmova, B., Kosova, E., & Stopkova, P. (2023). Virtual Reality Environment for Exposure Therapy in Obsessive-Compulsive Disorder: A Validation Study. Virtual Reality, 27, 2691-2701.[CrossRef
[17] Faulk, K., & Kameg, B. (2023). Diagnosis and Management of Perinatal Obsessive-Compulsive Disorder. The Journal for Nurse Practitioners, 19, Article ID: 104707.[CrossRef
[18] Fisher, P. L., & Wells, A. (2008). Metacognitive Therapy for Obsessive-Compulsive Disorder: A Case Series. Journal of Behavior Therapy and Experimental Psychiatry, 39, 117-132.[CrossRef] [PubMed]
[19] Gätmsiarz, F., & Crockett, M. J. (2015). Goal-Directed, Habitual and Pavlovian Prosocial Behavior. Frontiers in Behavioral Neuroscience, 9, Article No. 135.[CrossRef] [PubMed]
[20] Gillan, C. M., Morein-Zamir, S., Urcelay, G. P., Sule, A., Voon, V., Apergis-Schoute, A. M., Fineberg, N. A., Sahakian, B. J., & Robbins, T. W. (2014). Enhanced Avoidance Habits in Obsessive-Compulsive Disorder. Biological Psychiatry, 75, 631-638.[CrossRef] [PubMed]
[21] Hertenstein, E., Rose, N., Voderholzer, U., Heidenreich, T., Nissen, C., Thiel, N., Herbst, N., & Külz, A. K. (2012). Mindfulness-Based Cognitive Therapy in Obsessive-Compulsive Disorder—A Qualitative Study on Patients’ Experiences. BMC Psychiatry, 12, Article No. 185.[CrossRef
[22] Jalal, B., Brühl, A., O’Callaghan, C., Piercy, T., Cardinal, R. N., Ramachandran, V. S., & Sahakian, B. J. (2018). Novel Smartphone Interventions Improve Cognitive Flexibility and Obsessive-Compulsive Disorder Symptoms in Individuals with Contamination Fears. Scientific Reports, 8, Article No. 14923.[CrossRef] [PubMed]
[23] Javaherirenani, R., Mortazavi, S. S., Shalbafan, M., Ashouri, A., & Farani, A. R. (2022). Virtual Reality Exposure and Response Prevention in the Treatment of Obsessive-Compulsive Disorder in Patients with Contamination Subtype in Comparison with in Vivo Exposure Therapy: A Randomized Clinical Controlled Trial. BMC Psychiatry, 22, Article No. 740.[CrossRef] [PubMed]
[24] Kessler, R. C., Petukhova, M., Sampson, N. A., Zaslavsky, A. M., & Wittchen, H.-U. (2012). Twelve-Month and Lifetime Prevalence and Lifetime Morbid Risk of Anxiety and Mood Disorders in the United States: Anxiety and Mood Disorders in the United States. International Journal of Methods in Psychiatric Research, 21, 169-184.[CrossRef] [PubMed]
[25] Kvale, G., Hansen, B., Björgvinsson, T., Børtveit, T., Hagen, K., Haseth, S., Kristensen, U. B., Launes, G., Ressler, K. J., Solem, S., Strand, A., Van Den Heuvel, O. A., & Öst, L.-G. (2018). Successfully Treating 90 Patients with Obsessive Compulsive Disorder in Eight Days: The Bergen 4-Day Treatment. BMC Psychiatry, 18, Article No. 323.[CrossRef] [PubMed]
[26] McLauchlan, J., Thompson, E. M., Ferrão, Y. A., Miguel, E. C., Albertella, L., Marazziti, D., & Fontenelle, L. F. (2022). The Price of Love: An Investigation into the Relationship between Romantic Love and the Expression of Obsessive-Compulsive Disorder. CNS Spectrums, 27, 691-698.[CrossRef
[27] Miegel, F. S., Schröder, J., Schultz, J., Müller, J. C., & Jelinek, L. (2023). Expected Increase in Health Competence Improves over Modules of an Unguided Internet-Based Cognitive-Behavioural Therapy for Obsessive-Compulsive Disorder. International Journal of Psychology, 58, 443-448.[CrossRef] [PubMed]
[28] Miegel, F., Bücker, L., Kühn, S., Mostajeran, F., Moritz, S., Baumeister, A., Lohse, L., Blömer, J., Grzella, K., & Jelinek, L. (2022). Exposure and Response Prevention in Virtual Reality for Patients with Contamination-Related Obsessive-Com-pulsive Disorder: A Case Series. Psychiatric Quarterly, 93, 861-882.[CrossRef] [PubMed]
[29] Miegel, F., Demiralay, C., Moritz, S., Wirtz, J., Hottenrott, B., & Jelinek, L. (2020). Metacognitive Training for Obsessive-Compulsive Disorder: A Study Protocol for a Randomized Controlled Trial. BMC Psychiatry, 20, Article No. 350.[CrossRef] [PubMed]
[30] Myers, S. G., & Wells, A. (2005). Obsessive-Compulsive Symptoms: The Contribution of Metacognitions and Responsibility. Journal of Anxiety Disorders, 19, 806-817.[CrossRef] [PubMed]
[31] Öst, L.-G., Havnen, A., Hansen, B., & Kvale, G. (2015). Cognitive Behavioral Treatments of Obsessive-Compulsive Disorder. A Systematic Review and Meta-Analysis of Studies Published 1993-2014. Clinical Psychology Review, 40, 156-169.[CrossRef] [PubMed]
[32] Ou, W., Li, Z., Zheng, Q., Chen, W., Liu, J., Liu, B., & Zhang, Y. (2021). Association between Childhood Maltreatment and Symptoms of Obsessive-Compulsive Disorder: A Meta-Analysis. Frontiers in Psychiatry, 11, Article ID: 612586.[CrossRef] [PubMed]
[33] Paul, I., Saraf, G., Chandra, P. S., & Reddy, Y. C. J. (2020). Obsessive Compulsive-Disorder and Reproductive Life Events. Asian Journal of Psychiatry, 52, Article ID: 102124.[CrossRef] [PubMed]
[34] Robbins, T. W., Vaghi, M. M., & Banca, P. (2019). Obsessive-Compulsive Disorder: Puzzles and Prospects. Neuron, 102, 27-47.[CrossRef] [PubMed]
[35] Ruscio, A. M., Stein, D. J., Chiu, W. T., & Kessler, R. C. (2010). The Epidemiology of Obsessive-Compulsive Disorder in the National Comorbidity Survey Replication. Molecular Psychiatry, 15, 53-63.[CrossRef] [PubMed]
[36] Salkovskis, P. M. (1985). Obsessional-Compulsive Problems: A Cognitive-Behavioural Analysis. Behaviour Research and Therapy, 23, 571-583.[CrossRef] [PubMed]
[37] Salkovskis, P. M. (1999). Understanding and Treating Obsessive-Compulsive Disorder. Behaviour Research and Therapy, 37, S29-S52.
[38] Sánchez Escamilla, F., Redondo Delgado, M., Herrero, L., & Pérez Nieto, M. Á. (2023). Metanalysis of the Efficacy of Metacognitive Therapy and Acceptance and Commitment Therapy on Cognitive Intrusion. Current Psychology, 43, 8149-8157.[CrossRef
[39] Shin, N. Y., Lee, T. Y., Kim, E., & Kwon, J. S. (2014). Cognitive Functioning in Obsessive-Compulsive Disorder: A Meta-Analysis. Psychological Medicine, 44, 1121-1130.[CrossRef
[40] Stein, D. J., Costa, D. L. C., Lochner, C., Miguel, E. C., Reddy, Y. C. J., Shavitt, R. G., Van Den Heuvel, O. A., & Simpson, H. B. (2019). Obsessive-Compulsive Disorder. Nature Reviews Disease Primers, 5, Article No. 52.[CrossRef] [PubMed]
[41] Van Bennekom, M. J., De Koning, P. P., Gevonden, M. J., Kasanmoentalib, M. S., & Denys, D. (2021). A Virtual Reality Game to Assess OCD Symptoms. Frontiers in Psychiatry, 11, Article ID: 550165.[CrossRef] [PubMed]
[42] Wheaton, M. G., Patel, S. R., Andersson, E., Rück, C., & Simpson, H. B. (2021). Predicting Treatment Outcomes from Internet-Based Cognitive Behavior Therapy for Obsessive-Compulsive Disorder. Behavior Therapy, 52, 77-85.[CrossRef] [PubMed]
[43] Wootton, B. M., Karin, E., Dear, B. F., Staples, L., Nielssen, O., Kayrouz, R., & Titov, N. (2021). Internet-Delivered Cognitive-Behaviour Therapy (ICBT) for Obsessive-Compulsive Disorder When Delivered as Routine Clinical Care: A Phase IV Clinical Trial. Journal of Anxiety Disorders, 82, Article ID: 102444.[CrossRef] [PubMed]