可抗菌的海藻酸钠/棉纤维水凝胶纤维的制备与热稳定性研究

Preparation and Thermal Stability of Antibacterial Sodium Alginate/Cotton Fiber Hydrogel Fiber

摘要: 海藻酸钠(SA)以其来源广泛、价格低廉且毒性极低等特点在伤口敷料领域备受关注，但存在热稳定性差，抗菌性能差等缺点亟待解决。本研究以海藻酸钠为原料，加入粉碎至1 mm的棉纤维进行气动搅拌直至分散完全，得到纺丝原液，选取5 wt%的CaCl₂溶液为凝固浴，利用湿法纺丝机进行纺丝得到海藻酸钠/棉纤维水凝胶纤维，其拉伸强度可达1.22 MPa，热分解温度与纯海藻酸钠水凝胶纤维比提升了5.7%，使其具有更高的热稳定性。添加银纳米线增强其抗菌性能，当银纳米线浓度至0.09 mg/mL时抑菌圈直径最大，达到4 mm以上，在伤口敷料领域有良好的发展前景。

Abstract: Sodium alginate (SA) has attracted much attention in the field of wound dressings due to its wide source, low price, and extremely low toxicity. However, there are shortcomings such as poor thermal stability and poor antibacterial performance that need to be addressed urgently. In this study, sodium alginate was used as the raw material, and cotton fiber crushed to 1 mm was added for pneumatic stirring until complete dispersion to obtain the spinning stock solution. 5 wt% CaCl₂ solution was selected as the coagulation bath, and the wet spinning machine was used for spinning to obtain sodium alginate/cotton fiber hydrogel fiber, whose tensile strength reached 1.22 MPa, and the thermal decomposition temperature increased by 5.7% compared with pure sodium alginate hydrogel fiber, making it have higher thermal stability. Adding silver nanowires enhances its antibacterial properties. When the concentration of silver nanowires reaches 0.09 mg/mL, the diameter of the antibacterial zone reaches its maximum, reaching over 4 mm. It has good development prospects in the field of wound dressings.