香苏通降散治疗IBS-D (脾胃虚弱证)临床疗效观察

Clinical Effect of IBS-D (Spleen and Stomach Weakness)

摘要: 目的：观察香苏通降散对IBS-D (脾胃虚弱证)的临床疗效，进一步探究其机制。方法：本研究选择60名病人作为研究对象，这些病人均符合IBS-D脾胃虚弱证相关指征，随机分为人数相同的对照组与治疗组，一个疗程时间为一个月，评估两组病人在治疗前与治疗后的各项指标，判断分析药物取得的临床疗效。结果：1) 经对比后发现，治疗组病人经过治疗之后，所产生的总有效率为93.33%，对照组的总有效率为65.51%，两组相比较存在显著性差异(P < 0.05)，因此可以得出，临床采用香苏通降散具有更好的疗效。2) 对两组病人进行治疗之前，对比两组的症状总积分，不具有显著性差异；经过治疗之后，治疗组的症状总积分更加明显，两组之间存在显著性差异(P < 0.05)。3) 在医治前两组间的主要、次要症状积分进行对比无差异性(P > 0.05)，能进行后续的对比研究；治疗后两组的主症大便溏泄、腹痛和各项次症积分进行对比，各数据指标显示治疗组明显优于对照组，具有差异性(P < 0.05)，证实治疗组改善中医症状积分方面整体水平效果比对照组更加突出。结论：香苏通降散可以有效的对腹泻型肠易激综合征(脾胃虚弱证)进行诊治，明显的缓解病人的临床症状，提升生活质量，安全并且没有治疗副作用，值得广泛应用。

Abstract: Objective: To observe the clinical effect of IBS-D (spleen and stomach weakness syndrome) and further explore the mechanism. Methods: In this study, 60 patients were selected as the relevant indications of IBS-D spleen and stomach weakness, and were randomly divided into the control group with the same number and the treatment group. A treatment period was one month to evaluate the indicators before and after treatment, and judge the clinical efficacy of the drugs. Results: 1) After comparison, it was found that the total effective rate of the patients in the treatment group was 93.33%, and the total effective rate of the control group was 65.51%. There was a significant difference between the two groups (P < 0.05), so it can be concluded that the clinical use of PSA had better effect. 2) Before the treatment of the two groups, the total symptom score was not significantly different; after the treatment, the total symptom score of the treatment group was more obvious, and there was a significant difference between the two groups (P < 0.05). 3) Comparing the main and secondary symptoms between the two groups before the treatment (P > 0.05), with subsequent comparison study; comparing loose stools, abdominal pain and secondary disease points after treatment. The data indicators showed that the treatment group was significantly better than that of the control group, with difference (P < 0.05), confirming that the overall effect of the treatment group on improving the TCM symptoms was more prominent than that of the control group. Conclusion: It can effectively diagnose and treat diarrhea type irritable bowel syndrome (spleen and stomach weakness syndrome), obviously relieve the clinical symptoms of patients, improve the quality of life, be safe and have no treatment side effects, which is worthy of wide application.