探讨三参降消胶囊对2型糖尿病合并肥胖患者中医症状积分及血糖水平的影响

To Explore the Influence of Sanshen Jiangxiao Capsule on TCM Symptom Score and Blood Sugar Level of Type 2 Diabetes Patients with Obesity

摘要: 目的：探讨三参降消胶囊对2型糖尿病合并肥胖患者中医症状积分及血糖水平的影响。方法：此次研究对象抽选，为2022年1月~2023年12月就诊于院内的70例2型糖尿病合并肥胖患者，分为对照组与观察组各35例。所有患者均给予糖尿病基础治疗，对照组口服盐酸二甲双胍片治疗，观察组在对照组基础上联合三参降消胶囊进行治疗，对比2组治疗效果。结果：治疗前2组患者中医症候积分、血糖指标水平、血脂代谢指标水平、HOMA-IR与BMI指标对比，差异无统计学意义(P > 0.05)；治疗后2组患者中医症候积分、血糖指标水平、血脂代谢指标水平、HOMA-IR与BMI指标均呈下降趋势，且观察组中医症候积分、血糖指标水平、血脂代谢指标水平、HOMA-IR与BMI指标低于对照组，差异有统计学意义(P < 0.05)。观察组患者治疗有效率高于对照组，不良反应发生率低于对照组，差异具有统计学意义(P < 0.05)。结论：在对2型糖尿病合并肥胖患者进行治疗的过程中，采用三参降消胶囊对患者进行治疗，能够显著提升治疗有效率，同时能够有效改善患者的不良反应发生率；血糖、血脂指标；BMI指标以及HOMA-IR水平，在实际应用的过程中具有优良的效果，值得进一步的推广与应用。

Abstract: Objective: To explore the effect of Sanshen Jiangxiao capsule on TCM symptom score and blood sugar level of type 2 diabetes patients with obesity. Methods: In this study, 70 type 2 diabetes patients with obesity who were hospitalized from January 2022 to December 2023 were selected and divided into the control group and the observation group with 35 cases each. All patients were given basic treatment for diabetes. The control group was treated with metformin hydrochloride tablets, and the observation group was treated with Sanshen Jiangxiao capsule on the basis of the control group. The treatment effects of the two groups were compared. Results: There was no statistically significant difference (P > 0.05) in the scores of traditional Chinese medicine symptoms, blood glucose levels, lipid metabolism levels, HOMA-IR and BMI indicators between the two groups of patients before treatment; after treatment, the TCM syndrome score, blood glucose index level, blood lipid metabolism index level, HOMA-IR and BMI index of the two groups of patients showed a downward trend, and the observation group had lower TCM syndrome score, blood glucose index level, blood lipid metabolism index level, HOMA-IR and BMI index than the control group, with statistical significance (P < 0.05). The effective rate of treatment in the observation group was higher than that in the control group, and the incidence of adverse reactions was lower than that in the control group, with a statistically significant difference (P < 0.05). Conclusion: During the treatment of type 2 diabetes patients with obesity, the use of Shenjiangxiao capsule can significantly improve the treatment efficiency, and can effectively improve the incidence of adverse reactions of patients; blood glucose and lipid indicators; the BMI index and HOMA-IR level have excellent effects in practical application and are worthy of further promotion and application.