超声内镜引导细针穿刺抽吸术(EUS-FNA)在胰腺占位性病变中的诊断价值研究进展

Research Progress on the Diagnostic Value of Endoscopic Ultrasound-Guided Fine Needle Aspiration (EUS-FNA) in Pancreatic Space-Occupying Lesions

摘要: 胰腺占位性病变是常见的胰腺疾病，其中以胰腺癌最为常见。胰腺癌起病隐匿，早期缺乏典型的临床表现，大部分患者就诊时已失去了手术机会，只10%~20%的患者可以行手术切除，且5年生存率较低。因此，对胰腺微小占位的定性诊断尤为重要。胰腺是后腹膜脏器，位置较深，传统的B超、CT、MRI等影像学检查常由于受到腹壁脂肪及肠道气体的干扰，对胰腺的良恶性诊断敏感度低、特异度差。超声内镜可以清晰地显示病灶图像。超声内镜引导细针穿刺抽吸术(Endoscopic Ultraonography-Guided Fine-Needle Aspiration, EUS-FNA)可以将抽得的病变组织液和组织条送检做病理、生化和免疫学分析，为胰腺占位性病变的定性诊断提供重要的帮助。本文主要通过查阅近年来发表的文献分析近年来超声内镜引导细针穿刺抽吸术(EUS-FNA)在胰腺占位性病变中的诊断中的应用价值。

Abstract: Space occupying lesions of pancreas are common pancreatic diseases, among which pancreatic cancer is the most common. Pancreatic cancer has an insidious onset and lacks typical clinical manifestations in the early stage. Most patients have lost the opportunity for surgery at the time of treatment, and only 10% to 20% of patients can be surgically resected, and the 5-year survival rate is low. Therefore, the qualitative diagnosis of pancreatic microoccupation is particularly important. The pancreas is a posterior peritoneal organ with a deep location. Traditional B-ultrasound, CT, MRI and other imaging examinations are often interfered by abdominal fat and intestinal gas, so they have low sensitivity and poor specificity for the diagnosis of benign and malignant pancreas. Endoscopic ultrasound can clearly display the lesion image. Endoscopic ultraonography guided fine-needle aspiration (EUS-FNA) can aspiration pathological tissue fluid and tissue strips for pathological, biochemical, and immunological analysis. It provides important help for the qualitative diagnosis of pancreatic space occupying lesions. In this paper, the application value of endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) in the diagnosis of pancreatic space occupying lesions was analyzed by reviewing the literature published in recent years.