重症肺炎患者血小板相关参数变化趋势与预后的关系

The Relationship between the Changing Trend of Platelet-Related Parameters and Prognosis in Patients with Severe Pneumonia

摘要: 重症肺炎是呼吸与危重症医学科的一种常见的危重症感染性疾病。疾病特点为症状不典型，即患者不仅出现呼吸系统炎症、肺间质损伤等表现，或还伴随全身炎症反应，如高热、惊厥等；此病进展迅速、来势凶猛，且治疗费用昂贵、效果欠佳，死亡率居高不下，给患者及社会造成巨大的负担。早期识别疾病的发展趋势，评估患者病情严重程度并对其选取有效治疗措施，对降低患者致残率、病死率及合理利用医疗资源至关重要。但目前临床上还缺乏可以精准预测重症肺炎预后的常用指标。血小板相关参数对重症肺炎的预后评估的临床适用性及有效性尚存在争议。本文就血小板相关参数在重症肺炎患者病情评估中的作用进行综述，以帮助临床医生对重症肺炎进行更好评估及诊治。

Abstract: Severe pneumonia is a common critical infectious disease in the Department of Respiratory and Critical Care Medicine. The disease is characterized by atypical symptoms, that is, patients not only have respiratory system inflammation, pulmonary interstitial damage and other manifestations, or accompanied by systemic inflammatory reactions, such as high fever, convulsions, etc., the disease progresses rapidly, violently, and the treatment cost is expensive, the effect is not good, and the mortality rate remains high, causing a huge burden to patients and society. Early identification of the development trend of the disease, assessment of the severity of the patient’s disease and selection of effective treatment measures are essential to reduce the disability rate and mortality rate of patients and rationally use medical resources. However, there is still a lack of commonly used indicators that can accurately predict the prognosis of severe pneumonia. The clinical applicability and effectiveness of platelet-related parameters in the prognostic assessment of severe pneumonia are still controversial. This article reviews the role of platelet-related parameters in the assessment of patients with severe pneumonia, so as to help clinicians better evaluate, diagnose and treat severe pneumonia.