益生菌在根除幽门螺杆菌治疗中的研究进展

Research Progress of Probiotics in Helicobacter pylori Eradication Therapy

摘要: 幽门螺杆菌(Helicobacter pylori, H. pylori)是慢性感染性致病菌，与慢性胃炎、消化性溃疡、胃癌、胃黏膜相关淋巴组织(MALT)淋巴瘤等胃肠道疾病的发病直接关系。随着临床上抗生素治疗H. pylori的发展，H. pylori的耐药性逐渐提升，感染根治率逐渐下降，并带来较多治疗的不良反应。H. pylori根除疗法会导致患者肠道菌群失调，影响疾病康复。益生菌在调节肠道菌群方面具有重要作用，本文主要通过查阅近年来发表的文献分析益生菌在根除H. pylori治疗中的作用。

Abstract: Helicobacter pylori (Helicobacterpylori, H. pylori) is a chronic infectious pathogens, and chronic gastritis, peptic ulcer, gastric cancer, gastric mucosa associated lymphoid tissue (MALT) treated the onset of gastrointestinal diseases such as lymphoma. With the development of clinical antibiotic treatment of H. pylori, the resistance of H. pylori has gradually increased, the rate of radical treatment of infection has gradually decreased, and more adverse reactions have been brought about. H. pylori eradication therapy can cause intestinal flora imbalance in patients, affecting the recovery of the disease. Probiotics play an important role in regulating intestinal flora. This paper mainly analyzed the role of probiotics in eradicating H. pylori by referring to the literature published in recent years.