无梗阻性冠状动脉伴与不伴房颤的定量血流比差异

Quantitative Flow Ratio Difference in Non-Obstructive Coronary Arteries with and without Atrial Fibrillation

摘要: 目的：本研究旨在探讨QFR值在无梗阻性冠状动脉伴房颤患者中的准确性。方法：本研究一共纳入房颤患者40例和非房颤患者80例，分别测量两组患者的左前降支(LAD)、左回旋支(LCX)及右冠脉(RCA) QFR及AMR值进行统计分析。结果：两组患者左前降支、左回旋支及右冠脉的QFR值无显著差异，与对照组相比，研究组左回旋支的微血管阻力显著升高(P = 0.007)，研究组患者左前降支及右冠脉的微血管阻力较对照组稍高，但统计学无明显差异(P > 0.05)。结论：QFR对无梗阻性冠状动脉伴房颤患者的准确性需进一步探讨。

Abstract: Objective: The aim of this study was to investigate the accuracy of QFR in patients with non-obstructive coronary artery with atrial fibrillation. Methods: A total of 40 patients with atrial fibrillation and 80 patients without atrial fibrillation were included in this study. QFR and AMR values of left anterior descending branch (LAD), left circumflex branch (LCX) and right coronary artery (RCA) were measured respectively in the two groups for statistical analysis. Results: There were no significant differences in QFR values of left anterior descending branch, left circumflex branch and right coronary artery between the two groups. Compared with the control group, the microvascular resistance of left circumflex branch in the study group was significantly increased (P = 0.007), and the microvascular resistance of left anterior descending branch and right coronary artery in the study group was slightly higher than that of the control group, but there was no statistically significant difference (P > 0.05). Conclusion: The accuracy of QFR in patients with non-obstructive coronary artery with atrial fibrillation needs further investigation.