揿针联合中药直肠滴入对脾肾气虚兼血瘀型早期糖尿病肾病患者的临床疗效观察

Clinical Observation on the Treatment of Early Diabetic Nephropathy Syndrome of Qi Deficiency of Spleen and Kidney with Blood Stasis by Press-Needle Combined with Rectal Drip of Chinese Herbs

摘要: 目的：探讨揿针联合中药直肠滴入在治疗脾肾气虚兼血瘀型早期糖尿病肾病(DKD)的临床疗效。方法：选取本院收治脾肾气虚兼血瘀型早期DKD患者64例，分为对照组(32例)、揿针联合中药直肠滴入组(32例)，对照组给予胰岛素和口服降糖药控制血糖；揿针联合中药直肠滴入组在对照组治疗基础上给予中药直肠滴入联合揿针治疗，均治疗1疗程(14天)后，对比两组患者的临床疗效、肾功能指标、中医证候积分。结果：治疗前，两组患者临床疗效、肾功能指标、中医证候积分差异无统计学意义；治疗后，联合组中医证候积分优于对照组(P < 0.05)；联合组临床疗效、肾功能指标均优于对照组(P < 0.05)。结论：采用揿针联合中药直肠滴入治疗脾肾气虚兼血瘀型早期DKD患者，可有效改善患者症状，保护肾脏功能，临床疗效高于单一西药治疗。

Abstract: Objective: To investigate the clinical efficacy of press-needle combined with rectal administration of traditional Chinese medicine in the treatment of early diabetic kidney disease (DKD) with deficiency of spleen and kidney qi and concurrent blood stasis type. Methods: A total of 64 patients with early DKD of the spleen and kidney qi deficiency and blood stasis type admitted to our hospital were selected and divided into a control group (32 cases) and an press-needle combined with traditional Chinese medicine rectal administration group (32 cases). The control group was treated with insulin and oral hypoglycemic drugs to control blood sugar; the combined group was treated on the basis of the control group with traditional Chinese medicine rectal administration combined with press-needle. After one course of treatment (14 days), the clinical efficacy, renal function indicators, and traditional Chinese medicine syndrome scores of the two groups were compared. Results: Before treatment, there was no statistical significance in the clinical efficacy, renal function indicators, and traditional Chinese medicine syndrome scores between the two groups. After treatment, the combined group showed better traditional Chinese medicine syndrome scores than the control group (P < 0.05); the clinical efficacy and renal function indicators of the combined group were also better than those of the control group (P < 0.05). Conclusion: Press-needle combined with rectal administration of traditional Chinese medicine for patients with early DKD of the spleen and kidney qi deficiency and blood stasis type can effectively improve patient symptoms, protect renal function, and have higher clinical efficacy compared to single Western medicine treatment.