基于“肺为血脏”论治慢阻肺稳定期临证心得
Clinical Experience of Treating COPD in Stable Phase Based on the Theory of “Lung Is Blood Viscus”
摘要: 古代医家认为“肺为气之主”、“肺为水之上源”,鲜少提及“肺为血脏”。本人查阅大量文献及对临床病例进行观察,发现肺对于一身之血的生成及运行有决定性作用,因此肺脏不仅仅单纯为气脏,亦为血脏。该文从“肺为血脏”的理论角度浅析慢阻肺“久病必瘀”的致病特点,探讨活血化瘀为其稳定期的治疗原则,选用血府逐瘀汤进行治疗,增加慢阻肺稳定期的临床治疗新思路。
Abstract: Ancient doctors believed that “the lung is the Lord of gas” and “the lung is the upper source of water”, and rarely mentioned that “the lung is blood viscus”. The author consulted a large quantity of literature and observed clinical cases, and found that the lung played a decisive role in the generation and operation of blood, so the lung is not only gas, but also blood viscus. From the perspective of the theory of “lung is blood viscus”, the paper analyzes the pathogenic characteristics of COPD of “long-term illness will be blood stasis”, discusses the treatment principle of promoting blood circulation and removing blood stasis in its stable period, chooses Xuefu Zhuyu Decoction for treatment, and increases the new idea of clinical treatment of COPD in the stable phrase.
文章引用:刘瑞娟, 任存霞. 基于“肺为血脏”论治慢阻肺稳定期临证心得[J]. 中医学, 2024, 13(7): 1530-1535. https://doi.org/10.12677/tcm.2024.137234

参考文献

[1] 王玮, 龙杞, 岳国龙, 等. 中药治疗慢性阻塞性肺疾病的研究进展[J]. 中国医药导报, 2022, 19(30): 54-57.
[2] Chen, W., Xu, J.Y., et al. (2018) Prevalence and Risk Factors of Chronic Obstructive Pulmonary Disease in China (the China Pulmonary Health [CPH] Study): A National Cross-Sectional Study. The Lancet, 391, 1706-1717. [Google Scholar] [CrossRef
[3] Jarhyan, P., Hutchinson, A., Khaw, D., et al. (2022) Prevalence of Chronic Obstructive Pulmonary Disease and Chronic Bronchitis in Eight Countries: A Systematic Review and Meta-Analysis. Bulletin of the World Health Organization, 100, 216-230. [Google Scholar] [CrossRef
[4] 王静. 慢性阻塞性肺疾病发病机理及精准治疗研究进展[J]. 中国处方药, 2021, 19(7): 16-18.
[5] Tong, S., Chen, H., Cheng, G., et al. (2020) Metal-Organic Framework with Dual Functional Sites for CO2 Catalytic Fixation and Treatment on COPD by Down-Regulating the tlr3 Expression on the Lung Mucosal Epithelial Cells. Journal of Coordination Chemistry, 73, 1086-1096. [Google Scholar] [CrossRef
[6] 周义浪, 吴晓勇, 吴万垠. 基于《理虚元鉴》“肺脾二统”论治癌性疲乏[J]. 中医杂志, 2019, 60(13): 1161-1163.
[7] 吕东兴, 对《皇帝内经》中“宗气”的再认识[J]. 吉林中医药, 2011, 31(2): 95-96.
[8] Lefrancais, E., Ortiz-Munoz, G., Caudrillier, A., et al. (2017) The Lung Is a Site of Platelet Biogenesis and a Reservoir for Haematopoietic Progenitors. Nature, 544, 105-109. [Google Scholar] [CrossRef] [PubMed]
[9] 叶显纯. 《医方考》剖析[J]. 上海中医药杂志, 2007, 41(11): 240-242.
[10] 姚泰. 生理学[M]. 北京: 人民卫生出版社, 2003: 152.
[11] 曹鸿云. 咳嗽辨治体会[J]. 吉林中医药, 2011, 30(3): 213-214
[12] 中华医学会, 中华医学会杂志社, 中华医学会全科医学分会, 等. 慢性阻塞性肺疾病基层诊疗指南(2018) [J]. 中华全科医师杂志, 2018, 17(11): 856-870.
[13] 廖小明, 钟小兰. 活血化瘀法在慢性阻塞性肺疾病中的运用[J]. 中国民族民间医药, 2009, 15(9): 119-120.
[14] 李文辉. 肺胀与血瘀浅探[J]. 湖南中医药杂志, 1994, 10(4): 27-28.
[15] 吴剑宏, 陈幸谊. 血府逐瘀汤方剂的现代药理研究进展[J]. 中成药, 2013, 35(5): 1054-1058.
[16] 陈潮祖. 中医病机治法学[M]. 成都: 四川科学技术出版社, 1988: 16, 21.
[17] 贺照翠. 血府逐瘀汤加减治疗瘀血头痛的研究进展[J]. 中国实用药学, 2010, 5(5): 235-245.
[18] 王茹, 王培利, 王承龙. 血府逐瘀汤治疗冠状动脉粥样硬化性心脏病研究进展[J]. 辽宁中医杂志, 2019, 46(2): 432-435.
[19] 林建国, 姚魁武, 王擎擎, 等. 基于网络药理学和分子对接探讨血府逐瘀汤治疗心肌梗死的作用机制[J]. 中国中药杂志, 2021, 46(4): 885-893.
[20] 高建华. 血府逐瘀汤治疗喘证66例观察[J]. 黑龙江中医药, 1991(3): 22-23.
[21] 黄宏伟. 血府逐瘀汤对大鼠血液流变学的影响[J]. 甘肃中医, 2005, 18(4): 39-40.