慢性乙型病毒性肝炎合并疾病横断面分析

Cross-Sectional Analysis of Chronic Hepatitis B Complicated with Diseases

摘要: 目的：通过对昆明市第三人民医院的慢性乙型病毒型肝炎患者合并疾病情况，了解常见合并疾病，对于相关疾病进行早发现，早干预。方法：统计我院2022年9月~2023年8月期间诊断为“乙型肝炎病毒感染”或“乙型病毒性肝炎”，同时合并其他疾病的患者，根据分类整理分析得出相关结论。结果：本次研究共纳入1200例患者，其中男性806例(67.2%)，女性394例(32.8%)，CHB患者年龄段多集中在31~60岁(72.25%)。一共合并了417种疾病，最常见的合并疾病系统分类前五为消化系统疾病(160.83%)，内分泌、营养、代谢性疾病(107.92%)，血液系统疾病(64.08%)，症状、体征和异常化验结果(62.83%)，循环系统疾病(37.42%)。具体合并疾病前五为白细胞减少(22.33%)，肝纤维化(19.58%)，脾大(17.83%)，高氨血症(17.17%)，甲状腺结节(15.67%)。结论：慢性乙型病毒性肝炎合并疾病种类繁多，其中消化系统疾病和内分泌、代谢性疾病占比过高，应在治疗慢性乙型病毒性肝炎期间严格复查相关指标，警惕合并疾病，降低合并用药导致的毒副作用，进行早期预防，早发现，早干预，提高患者生活质量。

Abstract: Objective: To understand the common diseases associated with hepatitis B in the Third People’s Hospital of Kunming, and to detect and intervene the related diseases early. Methods: The patients diagnosed with “hepatitis B virus infection” or “hepatitis B virus infection” combined with other diseases in our hospital during September 2022 to August 2023 were counted, and relevant conclusions were drawn according to classification and analysis. Results: A total of 1200 patients were included in this study, including 806 males (67.2%) and 394 females (32.8%). CHB patients were mostly aged 31~60 years old (72.25%). A total of 417 diseases were combined, and the top five most common diseases were digestive system diseases (160.83%), endocrine, nutritional and metabolic diseases (107.92%), blood system diseases (64.08%), symptoms, signs and abnormal laboratory results (62.83%), and circulatory system diseases (37.42%). The top five diseases were leukopenia (22.33%), liver fibrosis (19.58%), splenomegaly (17.83%), hyperammonemia (17.17%) and thyroid nodules (15.67%). Conclusion: There are many kinds of diseases associated with hepatitis B, among which digestive system diseases and endocrine and metabolic diseases account for a high proportion. During the treatment of hepatitis B, we should strictly review the relevant indicators, be alert to the combined diseases, reduce the toxic and side effects caused by combined drugs, carry out early prevention, early detection, early intervention, and improve the quality of life of patients.