HIPK3在肿瘤学中的研究进展
Research Progress of HIPK3 in Oncology
DOI: 10.12677/acm.2024.1482178, PDF,   
作者: 孙泽辉:内蒙古医科大学第一临床医学院,内蒙古 呼和浩特
关键词: 蛋白激酶磷酸化调节miRNA调控肿瘤疾病Protein Kinase Phosphorylation Regulation miRNA Regulate Neoplastic Disease
摘要: 在癌症治疗和研究领域,激酶起着至关重要的作用。HIPK3广泛存在于人类和哺乳动物组织中。其参与的磷酸化调节、miRNA调控等是真核细胞凋亡、增殖、分化调节的重要一环,与多种疾病的发生、发展甚至肿瘤的耐药性亦存在着密切联系。本文拟对HIPK3的概念及其研究概况进行阐述,重点对其在肿瘤疾病的进展中发挥的生物学功能做一综述。
Abstract: In the field of cancer treatment and research, kinases play a crucial role. HIPK3 is widely found in human and mammalian tissues. Phosphorylation regulation and miRNA regulation are an important part of eukaryotic cell apoptosis, proliferation and differentiation regulation, and are closely related to the occurrence and development of many diseases and even drug resistance of tumors. In this paper, the concept and research status of HIPK3 are described, and the biological functions of HIPK3 in the progression of tumor diseases are reviewed.
文章引用:孙泽辉. HIPK3在肿瘤学中的研究进展[J]. 临床医学进展, 2024, 14(8): 34-40. https://doi.org/10.12677/acm.2024.1482178

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