外泌体在消化系统肿瘤早期诊断中的进展

Advances in Exosomes in the Early Diagnosis of Digestive System Tumor

摘要: 目的：总结外泌体在消化系统肿瘤(Digestive system tumor)早期诊断中的应用研究进展，为后续相关研究提供思路与方法，便于相关研究尽快转化为临床应用。方法：阅读国内外外泌体在消化系统肿瘤研究的相关文献，进行整理、总结并综述。结果：目前，消化系统肿瘤是当前肿瘤相关死亡常见的病因之一且发病年龄趋年轻化。外泌体(Exosomes)可在分子间通讯发挥巨大作用，对外泌体的检测可达到对消化系统肿瘤的早期诊断，这对于该类肿瘤患者的治疗及预后有重要意义。结论：外泌体检测在消化系统肿瘤早期诊断是可行的，相关研究方法与技术正在向临床应用转化。

Abstract: Objective: To summarize the research progress on the application of exosomes in the early diagnosis of digestive system tumors, to provide ideas and methods for the subsequent related research, and to facilitate the translation of related research into clinical application as soon as possible. Methods: The literatures related to the study of exosomes in digestive system tumors at home and abroad were reviewed, organized, summarized and synthesized. Results: Currently, digestive system tumors are the most common cause of tumor-related deaths and the age of onset tends to be younger. Exosomes can play a huge role in intermolecular communication, detection of exosomes can achieve early diagnosis of digestive system tumors, which is important for the treatment and prognosis of patients with this type of tumor. Conclusions: Exosome detection is feasible in the early diagnosis of digestive system tumors, and the related research methods and techniques are being translated into clinical applications.