犬颈下皮肤组织细胞瘤1例
A Case of Canine Cutaneous Histiocytoma under Neck Skin
摘要:
报告1例犬颈下皮肤组织细胞瘤病例。患病动物为7岁雄性斗牛犬,发现颈下皮肤包块一个多月后送医就诊。经手术切除肿块后固定送检,常规H&E染色后,组织学检查结果发现肿块内有大量肿瘤细胞成分,多为成纤维样细胞和组织细胞样细胞,部分肿瘤细胞团块间散在分布有充满血液的窦状腔隙,但是无内皮细胞包围,某些肿瘤细胞内有含铁血黄素沉积。诊断为皮肤组织细胞瘤。
A case of canine cutaneous histiocytoma under neck skin is reported. A 7-year-old male bulldog was present- ed with a firm subcutaneous nodule under neck skin for more than 1 month. Histopathological examination showed masses of tumor cells consisting of fibroblast- and histiocyte-like cells containing haemosiderin, and there were multi- focal areas of irregular cavities in the masses full of red cells without endothelial lining. These findings were consistent with all histiocytoma.
参考文献
[1]
|
张仕杰, 杨志贤. 犬皮肤型圆形细胞瘤之细胞学与组织学特征[J]. 中华民国兽医学会杂志, 1995, 25: 139-152.
|
[2]
|
P. F. Moore. Characterization of cytoplasmic lysozyme immuno- reactivity as a histiocytic marker in normal canine tissues. Veterinary Pathology, 1986, 23(6): 763-769.
|
[3]
|
P. F. Moore, M. D. Schrenzel, V. K. Affolter, et al. Canine cutaneous histiocytoma is an epidermotropic langerhans cell histiocytosis that expresses CD1 and specific beta 2-integrin molecules. American Journal of Pathology, 1996, 148(5): 1699-1707.
|
[4]
|
J. C. Conroy. Canine skin tumor. Journal of the American Animal Hospital Association, 1983, 19: 91-114.
|
[5]
|
G. H. Muller, R. W. Kirk and D. W. Scott. Histiocytoma. Small animal dermatology. 3rd Edition, Philadlphia: W.B. Saunders Co., 1983: 757.
|
[6]
|
W. M. Bender, G. H. Muller. Multiple, resolving, cutaneous histiocytoma in a dog. Journal of the American Veterinary Medical Association, 1989, 194(4): 535-537.
|
[7]
|
B. N. Bonnett, A. Egenva II and P. Olson. Mortality in insured Swedish dogs: Rates and causes of death in various breeds. Veterinary Research, 1997, 141(2): 40-44.
|