扶正抑癌类中药治疗结直肠癌的研究进展

Research Progress of Fuzhengyiai Chinese Medicine in the Treatment of Colorectal Cancer

摘要: 结直肠癌，也被称为大肠癌，是我国乃至全球发病率名列前茅甚至逐年攀升的消化道恶性肿瘤。2015年我国肿瘤登记地区，癌症总体死亡率构成前五位的依次是：肺癌(27.16%)、肝癌(13.97%)、胃癌(12.73%)、食管癌(8.39%)和结直肠癌(7.86%)，这表明大肠癌对人民的健康威胁不容小觑。针对结直肠癌的中西医治疗，西医治疗目前主要以手术作为根治方法为主，配合术后相关放疗以及化疗作为辅助治疗；中医治疗目前在国家大力发展推广中医药的情况下越来越受到重视，各种论治方法也层出不穷，近年来立足于“活血化瘀”、“健脾渗湿”、“扶正抑癌”等中医治疗原则治疗结直肠癌的研究取得不小进展，笔者将从“扶正抑癌”入手，整理归纳该类治疗原则中所应用的相关中药及其作用机制如何运用到大肠癌的预防、治疗之中。

Abstract: Colorectal cancer, also known as colorectal cancer, is a malignant tumor of digestive tract with the highest incidence in China and even in the world. In China’s tumor registration areas in 2015, the top five overall cancer mortality rates were: lung cancer (27.16%), liver cancer (13.97%), stomach cancer (12.73%), esophageal cancer (8.39%) and colorectal cancer (7.86%), which indicates that colorectal cancer is a health threat to the people. For the treatment of colorectal cancer, Western medicine is mainly based on surgery as a radical treatment, with postoperative radiotherapy and chemotherapy as auxiliary treatment. Traditional Chinese medicine treatment is currently in the state to vigorously develop and promote the case of more and more attention, a variety of treatment methods are emerging in an endless stream, in recent years based on the “blood circulation and stasis”, “spleen moisture”, “Fuzheng cancer suppression” and other traditional Chinese medicine treatment principles of the treatment of colorectal cancer research have made no small progress. The author will start from “Fuzheng cancer suppression”, to summarize the relevant Chinese medicine used in the treatment principles and how to apply the mechanism of action to the prevention and treatment of colorectal cancer.