Kim, C., MacKellar, W.C., Cho, N.M., Byrn, S.R. and Morré, D.J. (1997) Impermeant antitumor sulfonylurea conjugates that inhibit plasma membrane NADH oxidase and growth of HeLa cells in culture. Identification of binding proteins from sera of cancer patients. Biochimica et Biophysica Acta, 1324, 171-181.
http://dx.doi.org/10.1016/S0005-2736(96)00219-2
被以下文章引用:
-
标题:
磺酰脲类化合物抗肿瘤活性的研究进展The Development of Anti-Tumor Activity of Sulfonylurea Compounds
作者:
田静, 钱宇, 常霄巍, 巴俊杰
关键字:
磺酰脲, 抗肿瘤, 研究进展Sulfonylureas, Anti-Tumor, Development
期刊名称:
《Hans Journal of Medicinal Chemistry》, Vol.3 No.3, 2015-08-03
摘要:
在进一步探讨磺酰脲类化合物除草作用和降糖活性的同时,其抗肿瘤活性早已引起了人们的特别关注。磺酰脲类化合物有可能作为一类新兴的具有前景的抗肿瘤药物应用于医药领域,本文综述了国内外对该类化合物抗肿瘤活性的研究进展,以期对磺酰脲类抗肿瘤化合物的应用发展提供参考。
While the hypoglycemic and herbicidal activity of sulfonylurea is investigated, its anti-tumor ac-tivity has attracted special attention. Sulfonylurea compounds may be used in the medical field as a new class of promising anticancer drugs. In order to provide a reference for the application and development of anti-tumor sulfonylurea compounds, we summarize the domestic and foreign research progress of antitumor activity of the compounds.