标题:
人脐带间充质干细胞移植在神经系统疾病中的新进展The Latest Application Progress of Human Umbilical Cord-Derived Mesenchymal Stem Cells (hUC-MSCs) in
Neurological Diseases
作者:
张德双, 陈娟
关键字:
人, 脐带, 间充质干细胞, 移植, 神经系统疾病Human; Umbilical Cord; Mesenchymal Stem Cells; Transplantation; Nervous System Diseases
期刊名称:
《International Journal of Psychiatry and Neurology》, Vol.1 No.3, 2012-08-30
摘要:
人脐带组织富含间充质干细胞(MSCs)，与其他来源的MSCs相比，具有来源丰富、容易提取、倍增时间短、免疫原性低、移植后长期存活、不涉及伦理问题等多种优点，近年来对其研究越来越多。在适宜的环境下，人脐带间充质干细胞(hUC-MSCs)可以分化为神经样细胞，移植于多种神经系统疾病动物模型后均可促进其神经功能恢复，现就此方面的最新研究及应用进展予以综述。
The mesenchymal stem cell is rich in human umbilical cord, compared with MSCs of other sources, hUC-MSCs have major advantages such as richer source, easier collection freedom, shorter doubling time, lower immunogenicity, longer-term survival after transplantation, no ethical implications and so on. In recent years, the investigation of hUC-MSCs has been growing. In appropriate circumstances, hUC-MSCs can differentiate into neuron-like cells, when transplanted into different animal models of neurological diseases can promote the recovery of neural function. Now, we will review the latest application progress of hUC-MSCs in Neurological Diseases.