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R. P. Goddeau Jr., S. B. Silverman and J. R. Sims. Dexmedetomidine for the treatment of paroxysmal autonomic instability with dystonia. Neurocritical Care, 2007, 7(3): 217-220.


  • 标题: 病毒性脑炎所致阵发性自主神经性不稳伴肌张力不全1例Paroxysmal Autonomic Instability with Dystonia Induced by Viral Encephalitis: A Case Report

    作者: 易招师, 查剑, 钟建民, 吴华平, 虞雄鹰, 陈勇

    关键字: 病毒性脑炎, 自主神经功能不稳, 肌张力不全Viral Encephalitis; Autonomic Instability; Dystonia

    期刊名称: 《Asian Case Reports in Pediatrics》, Vol.1 No.3, 2013-08-01

    摘要: 目的:探讨病毒性脑炎所致阵发性自主神经性不稳伴肌张力不全(PAID)的临床特点及治疗对策。方法:回顾性分析本院收治的1例病毒性脑炎所致PAID的临床资料。结果:患儿出现阵发性躁动、发热、多汗、呼吸急促、心动过速、血压升高、肌张力障碍和抽搐症状,经联合用药治疗后,患儿逐步好转出院,随访1年半,四肢肌张力恢复正常,未遗留下严重后遗症状。结论:由病毒性脑炎所致的PAID较少见,应注意早期识别,积极控制PAID症状,宜尽早联合两种或两种以上药物治疗。 Objective: To explore the clinical features and therapeutic strategy of Paroxysmal autonomic instability with dystonia (PAID) induced by viral encephalitis. Methods:The clinical data of one child with PAID induced by viral encephalitis diagnosed in our hospital was analyzed retrospectively. Results: The child presented with intermittent agitation, fever,diaphoresis, tachycardia,tachypnea, hypertension, extensor posturing and seizures.Through the treatment of combined drugs, the child was gradually improved and discharged.After a follow-up of one and a half years, themuscular tension of limbs returned to normal and there were not serious neurologic sequelae. Conclusion: The PAID induced by viral encephalitis is rare. Early recognition is of paramount importance to start treatment in an early stage and various drugs should be combined to alleviate PAID.