标题:
黄芪组分及主要成分保肝作用研究进展Progress in Hepatoprotective Effect of Main Compositions in Astragali Radix
作者:
孟琮, 吴家胜, 马越鸣
关键字:
黄芪, 保肝, 黄芪总黄酮, 黄芪总皂苷, 黄芪多糖, 有效成分Astragali Radix, Hepatoprotective Effect, Astragalosides, Total Flavonoids of Astragali Radix, Astraglus Polysaccharide, Active Constituents
期刊名称:
《Traditional Chinese Medicine》, Vol.5 No.2, 2016-05-30
摘要:
黄芪为中医临床常用保肝中药之一，研究表明其有效组分及主要成分对肝损伤具有保护作用。本文从抗肝纤维化、肝缺血再灌注、免疫性肝损伤、肝癌、乙肝病毒感染等方面，对黄芪有效组分(包括黄芪总皂苷、黄芪总黄酮及黄芪多糖)和主要成分(包括黄芪甲苷、芒柄花素和毛蕊异黄酮)的保肝作用及可能机制进行综述，为黄芪的进一步研发和临床应用提供参考。
Astragali Radix is one of the commonly used Traditional Chinese Medicines for treatment of liver diseases in clinic. It has been reported that its main components and constituents had a protective effect on multiple liver injury. This article reviews the protective effect and mechanism of main components including astragalosides, total flavonoids of Astragali Radix, astraglus polysaccharide and constituents including astragaloside IV, formononetin, calycosin on liver injury such as liver fibrosis, liver ischemia and reperfusion injury, immunological liver injury, hepatoma and hepatitis B, so that to provide reference for further research and clinical application.