BR  >> Vol. 5 No. 3 (May 2016)

    Advances in Molecular Regulation of Artemisinin Biosynthesis

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李杉:华南理工大学生物科学与工程学院,广东 广州

青蒿青蒿素生物合成关键酶分子调控Artemisia annua L. Artemisinin Biosynthesis Key Enzymes Molecular Regulation



Artemisinin, a sesquiterpene lactone compound with an endoperoxide bridge, is a new and the most potent antimalarial drug. Commercially available artemisinin is extracted from Artemisia annua L. plants. Therefore, the regulation of artemisinin biosynthesis in Artemisia annua has be-come a hot spot. This paper reviews the ways of artesunate biosynthesis, especially the key enzymes and gene regulation in the biosynthesis. The review also presents the advances in molecular regulation of artemisinin biosynthesis, it focuses on how to enhance the artemisinin content to help stabilize the supply of artemisinin.

王路尧, 张颖, 唐克轩, 李杉, 赵静雅. 青蒿素生物合成分子调控研究进展[J]. 植物学研究, 2016, 5(3): 113-123.


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