脂质体制备工艺的研究进展
Research Progress of Liposome Preparation Technology
DOI: 10.12677/HJMCe.2022.102014, PDF,    科研立项经费支持
作者: 刘 璐, 贾殿隆：聊城大学药学院，山东 聊城
关键词: 脂质体；纳米材料；药物递送；脂质体的制备工艺；Liposomes； Nanomaterials； Drug Delivery； Preparation Technology of Liposomes
摘要: 脂质体作为药物递送的良好载体，其制备工艺距今约有半个多世纪的研究历史。实验室层面的脂质体制备技术已趋于成熟，现阶段的研究主要着眼于脂质体的制备由实验室至工业生产的过渡，若攻克此壁垒，将迎来脂质体药物上市的春天。本文将从脂质体制备技术的传统和非传统两个方面进行介绍，总结每个大类下的研究进展，为实验中涉及脂质体制备的科研工作者提供帮助。
Abstract: As a good carrier for drug delivery, liposomes have a research history of more than half a century in the preparation process. The liposome preparation technology at the laboratory level has become mature, and the current research mainly focuses on the transition of liposome preparation from la-boratory to industrial production. If this barrier is overcome, it will usher in the spring of liposome drug listing. This article will introduce the traditional and non-traditional aspects of liposome preparation technology, summarize the research progress under each category, and provide help for scientific researchers involved in the preparation of liposomes.
文章引用：刘璐, 贾殿隆. 脂质体制备工艺的研究进展[J]. 药物化学, 2022, 10(2): 144-152. https://doi.org/10.12677/HJMCe.2022.102014

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