中药鹅不食草中有效成分对过敏性鼻炎药理作用研究进展

Research Progress of the Pharmacological Action of the Effective Components in Centipeda minima on Allergic Rhinitis

摘要: 鹅不食草作为一种应用前景广阔的中药，在国内临床中多用于鼻咽癌、病毒性感染、软组织损伤等疾病的治疗。近年来。过敏性鼻炎在我国各年龄段人群普遍多发，患者除鼻腔感到不适之外，过敏性鼻炎还可能导致出现一系列并发症，如哮喘、鼻窦炎、结膜炎等，给人们的生活带来了极大的影响。相比采用外科手术和西药治疗，现临床治疗上更倾向于使用中药进行过敏性鼻炎的治疗。在国内的古方和少数民族药方中，鹅不食草是治疗过敏性鼻炎的一味常见药，全草可以直接入药，也可与辛夷花，苍耳子等其他中药进行配伍联合治疗鼻炎。随着检测手段和设备的发展，鹅不食草的化学成分及其药理活性逐渐阐明。本文就鹅不食草中的化学成分研究及鹅不食草在治疗过敏性鼻炎中的作用机理进行综述。

Abstract: As a kind of traditional Chinese medicine with broad application prospects, Centipeda minima is mostly used in the treatment of nasopharyngeal carcinoma, viral infection, soft tissue injury and other diseases in domestic clinical practice. In recent years, allergic rhinitis is common in people of all ages in China. In addition to nasal discomfort, patients with allergic rhinitis may also lead to a series of complications, such as asthma, sinusitis, conjunctivitis, etc., which have a great impact on people’s lives. Compared with surgery and Western medicine, the current clinical treatment is more inclined to use traditional Chinese medicine for the treatment of allergic rhinitis. Among the ancient prescriptions and ethnic minority prescriptions in China, Centipeda minima is a common medicine for the treatment of allergic rhinitis. The whole herb can be directly used as medicine, and can also be combined with magnolia flower, Fructus Xanthii and other traditional Chinese medicines to treat rhinitis. With the development of detection methods and equipment, the chemical components and pharmacological activities of Centipeda minima are gradually clarified. In this paper, the chemical constituents of Centipeda minima and the mechanism of Centipeda minima in the treatment of allergic rhinitis were reviewed.