针刺治疗格林–巴利综合征发病机制的研究进展

Research Progress on the Pathogenesis of Guillain-Barre Syndrome Treated with Acupuncture

摘要: 格林–巴利综合征(GBS)作为一种自身免疫性周围神经病，其主要临床表现为急性对称性弛缓性肢体瘫痪及感觉障碍的多样性。目前研究表明，GBS的发病不仅由免疫介导的神经损伤所触发，还与感染、遗传及环境因素紧密相关。西医具有具体的治疗方法，但伴随的风险如血液传播性疾病和低蛋白血症等不容忽视。近年来，针刺治疗在GBS的治疗中逐渐凸显其独特疗效，尤其在改善患者神经功能、缓解疼痛等方面成效显著。本文全面回顾了近年来针刺疗法在治疗领域的研究进展。这一综述将重点探讨针刺如何通过调节免疫系统、促进神经再生与修复以及改善疼痛症状来发挥其治疗作用，旨在深入解析针刺对GBS的治疗机制，为临床应用提供坚实的理论依据。

Abstract: Guillain-Barre syndrome (GBS), as an autoimmune peripheral neuropathy, is characterized by acute symmetrical flaccid limb paralysis and diverse sensory disorders. Current research suggests that the pathogenesis of GBS is triggered not only by immune-mediated nerve damage, but also closely related to infections, genetics, and environmental factors. Western medicine has specific treatment methods, but the risks accompanying it, such as blood-borne diseases and hypoalbuminemia, cannot be ignored. In recent years, acupuncture treatment has gradually demonstrated its unique effectiveness in the treatment of GBS, especially in improving patients’ neurological function and relieving pain, with significant results. This paper comprehensively reviewed recent progress of acupuncture in the treatment of GBS. This review will focus on how acupuncture plays its therapeutic effect by regulating the immune system, promoting nerve regeneration and repair, and improving pain symptoms. It aims to deeply analyze the therapeutic mechanism of acupuncture on GBS and provide a solid theoretical basis for clinical application.