间充质干细胞治疗在椎间盘退变中的研究与应用进展
Research and Application Progress of Mesenchymal Stem Cell Therapy in Intervertebral Disc Degeneration
摘要: 椎间盘退变是一种严重影响患者生活质量的疾病，其治疗一直是医学研究的热点。近年来，间充质干细胞因具有多向分化、免疫调节和分泌细胞因子等的能力，在治疗椎间盘退变方面展现出巨大潜力。本文通过检索了知网、万方、维普、Pubmed等数据库近3年来国内外相关研究文献，综述了间充质干细胞治疗椎间盘退变的最新研究进展，包括其作用机制、治疗效果及临床应用等方面，目的在于为未来间充质干细胞治疗椎间盘退变的研究及临床应用方面提供参考依据。
Abstract: Intervertebral disc degeneration is a disease that seriously affects the quality of life of patients. Its treatment has always been a hot spot in medical research. In recent years, mesenchymal stem cells have shown great potential in the treatment of intervertebral disc degeneration due to their abilities of multi-directional differentiation, immune regulation and secretion of cytokines. This article reviews the latest research progress of mesenchymal stem cells in the treatment of intervertebral disc degeneration by retrieving relevant research literatures at home and abroad in the past three years from databases such as CNKI, Wanfang, VIP and Pubmed, including its mechanism of action, therapeutic effect and clinical application. The purpose is to provide a reference for the research and clinical application of mesenchymal stem cells in the treatment of intervertebral disc degeneration in the future.
文章引用：周鑫, 皮雅雯. 间充质干细胞治疗在椎间盘退变中的研究与应用进展[J]. 临床医学进展, 2024, 14(12): 148-157. https://doi.org/10.12677/acm.2024.14123060

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