氢吗啡酮在区域阻滞麻醉中的临床应用进展

Progress in Clinical Application of Hydromorphone in Regional Block Anesthesia

摘要: 氢吗啡酮具有镇痛效果好、起效快、副作用相对较小等优势。在区域阻滞麻醉的临床应用中，氢吗啡酮与局麻药复合使用在外周神经阻滞、椎管内麻醉和分娩镇痛中均展现出良好效果，可显著增强麻醉效果，延长镇痛时间，但氢吗啡酮的应用也存在一定的安全性与局限性。近期氢吗啡酮与局麻药混合使用在区域麻醉的临床研究日益增多，所以本文拟综述氢吗啡酮与局麻药混合使用在临床的进展。

Abstract: Hydromorphone has the advantages of good analgesic effect, rapid onset of action, and relatively few side effects. In the clinical application of regional block anesthesia, hydromorphone combined with local anesthetics has shown good effects in peripheral nerve block, intraspinal anesthesia and labor analgesia, which can significantly enhance the anesthetic effect and prolong the analgesic time. However, there are some safety and limitations in the application of hydromorphone. Recently, there are more and more clinical studies on the combination of hydromorphone and local anesthetics in regional anesthesia. Therefore, this article reviews the clinical progress of the combination of hydromorphone and local anesthetics.