慢性阻塞性肺疾病合并认知障碍的研究进展
Progress in Chronic Obstructive Pulmonary Disease Associated with Cognitive Impairment
DOI: 10.12677/md.2024.144062, PDF,   
作者: 杜梦晴:济宁医学院临床医学院,山东 济宁;孔维香:济宁市第一人民医院,临床药学科,山东 济宁
关键词: 慢性阻塞性肺疾病认知功能认知障碍认知干预Chronic Obstructive Pulmonary Disease Cognitive Function Cognitive Impairment Cognitive Intervention
摘要: 认知障碍(cognitive impairment, CI)是慢性阻塞性肺疾病(COPD)患者的常见合并症,显著影响健康和临床结局。然而,它在很大程度上被忽视。本文旨在探讨COPD合并CI其流行病学特点、影响因素及干预措施等方面的研究进展,强调了早期检测和干预的必要性,以预防或延迟患者CI的发作或进展,为临床诊治提供参考。
Abstract: Cognitive impairment (CI) is a common comorbidity in patients with chronic obstructive pulmonary disease (COPD), which significantly affects health and clinical outcomes. However, it has been largely overlooked. The purpose of this article is to discuss the research progress of COPD complicated with CI, its epidemiological characteristics, influencing factors and interventions, and emphasize the necessity of early detection and intervention to prevent or delay the onset or progression of CI in patients, and provide reference for clinical diagnosis and treatment.
文章引用:杜梦晴, 孔维香. 慢性阻塞性肺疾病合并认知障碍的研究进展[J]. 医学诊断, 2024, 14(4): 426-431. https://doi.org/10.12677/md.2024.144062

参考文献

[1] Kahnert, K., Jörres, R.A., Behr, J. and Welte, T. (2023) The Diagnosis and Treatment of COPD and Its Comorbidities. Deutsches Ärzteblatt international, 120, 434-444. [Google Scholar] [CrossRef
[2] 卢凤达, 闫芸芸, 周靓, 等. 轻度认知障碍的早期诊断及筛查方法研究现状[J]. 中华老年医学杂志, 2024, 43(4): 528-533.
[3] 胡先纬, 涂友慧, 祝清清, 等. 慢性阻塞性肺疾病病患的认知功能探讨[J]. 临床肺科杂志, 2020, 25(4): 505-509.
[4] 宋歌. 老年慢性阻塞性肺疾病患者认知衰弱风险预测模型的构建及验证[D]: [硕士学位论文]. 太原: 山西医科大学, 2022.
[5] Xie, F. and Xie, L. (2019) COPD and the Risk of Mild Cognitive Impairment and Dementia: A Cohort Study Based on the Chinese Longitudinal Health Longevity Survey. International Journal of Chronic Obstructive Pulmonary Disease, 14, 403-408. [Google Scholar] [CrossRef] [PubMed]
[6] Roncero, C., Campuzano, A., Quintano, J., Molina, J., Pérez, J. and Miravitlles, M. (2016) Cognitive Status among Patients with Chronic Obstructive Pulmonary Disease. International Journal of Chronic Obstructive Pulmonary Disease, 11, 543-551. [Google Scholar] [CrossRef] [PubMed]
[7] Yohannes, A.M., Chen, W., Moga, A.M., Leroi, I. and Connolly, M.J. (2017) Cognitive Impairment in Chronic Obstructive Pulmonary Disease and Chronic Heart Failure: A Systematic Review and Meta-Analysis of Observational Studies. Journal of the American Medical Directors Association, 18, 451.e1-451.e11. [Google Scholar] [CrossRef] [PubMed]
[8] Ouellette, D.R. and Lavoie, K. (2017) Recognition, Diagnosis, and Treatment of Cognitive and Psychiatric Disorders in Patients with COPD. International Journal of Chronic Obstructive Pulmonary Disease, 12, 639-650. [Google Scholar] [CrossRef] [PubMed]
[9] Morris, C., Mitchell, J.W., Moorey, H., Younan, H., Tadros, G. and Turner, A.M. (2019) Memory, Attention and Fluency Deficits in COPD May Be a Specific Form of Cognitive Impairment. ERJ Open Research, 5, 1-9. [Google Scholar] [CrossRef] [PubMed]
[10] Dal Negro, R., Bonadiman, L., Tognella, S., Briccolo, F. and Turco, P. (2014) Extent and Prevalence of Cognitive Dysfunction in Chronic Obstructive Pulmonary Disease, Chronic Non-Obstructive Bronchitis, and in Asymptomatic Smokers, Compared to Normal Reference Values. International Journal of Chronic Obstructive Pulmonary Disease, 9, 675-683. [Google Scholar] [CrossRef] [PubMed]
[11] Baird, C., Lovell, J., Johnson, M., Shiell, K. and Ibrahim, J.E. (2017) The Impact of Cognitive Impairment on Self-Management in Chronic Obstructive Pulmonary Disease: A Systematic Review. Respiratory Medicine, 129, 130-139. [Google Scholar] [CrossRef] [PubMed]
[12] 戈艳蕾, 刘聪辉, 余华丽, 等. COPD伴或不伴低氧血症患者血清白介素-17与8-异前列腺素F2α及认知功能损伤情况研究[J]. 临床肺科杂志, 2019, 24(2): 251-254.
[13] 罗丽, 何正光, 王述红. 老年慢性阻塞性肺疾病伴低氧血症血清相关指标与认知功能损伤的关系[J]. 老年医学与保健, 2020, 26(6): 1013-1017.
[14] Tudorache, E., Fildan, A.P., Frandes, M., Dantes, E. and Tofolean, D.E. (2017) Aging and Extrapulmonary Effects of Chronic Obstructive Pulmonary Disease. Clinical Interventions in Aging, 12, 1281-1287. [Google Scholar] [CrossRef] [PubMed]
[15] 孙元, 肖强, 杨永强. 慢性阻塞性肺疾病患者血清炎症因子与认知功能障碍关系研究[J]. 中国社区医师, 2022, 38(29): 91-93.
[16] 岳森, 秦璟璟, 常晶. 慢阻肺患者继发认知功能障碍的影响因素[J]. 中国卫生工程学, 2023, 22(2): 220-222.
[17] van Beers, M., Janssen, D.J.A., Gosker, H.R. and Schols, A.M.W.J. (2018) Cognitive Impairment in Chronic Obstructive Pulmonary Disease: Disease Burden, Determinants and Possible Future Interventions. Expert Review of Respiratory Medicine, 12, 1061-1074. [Google Scholar] [CrossRef] [PubMed]
[18] 滕小华, 郭建英. 慢阻肺急性加重期患者治疗依从性差的相关因素分析和延续性护理干预措施[J]. 中国全科医学, 2019, 22(S2): 205-207.
[19] 曾小艺, 杨添文, 黄倩, 等. 慢性阻塞性肺疾病重度-极重度稳定期与急性加重期患者肺康复研究进展[J]. 中国现代医药杂志, 2021, 23(1): 93-98.
[20] 汪春荣, 刘勇, 詹亚峰, 等. 亚临床认知障碍慢性阻塞性肺疾病患者脑白质改变基于体系分析统计学分析[J]. 中国医药导报, 2020, 17(13): 114-117.
[21] Kaygusuz, M.H., Oral Tapan, O., Tapan, U. and Genc, S. (2022) Balance Impairment and Cognitive Dysfunction in Patients with Chronic Obstructive Pulmonary Disease under 65 Years. The Clinical Respiratory Journal, 16, 200-207. [Google Scholar] [CrossRef] [PubMed]
[22] 闫俊, 高亚亚, 史雅锋, 等. 慢性阻塞性肺疾病患者长期家庭氧疗对肺功能及认知功能影响的研究[J]. 临床神经病学杂志, 2022, 35(6): 412-416.
[23] Heslop-Marshall, K., Baker, C., Carrick-Sen, D., Newton, J., Echevarria, C., Stenton, C., et al. (2018) Randomised Controlled Trial of Cognitive Behavioural Therapy in COPD. ERJ Open Research, 4, 1-11. [Google Scholar] [CrossRef] [PubMed]
[24] Seok, J., Kim, G. and Kim, J.U. (2024) Comparative Efficacy of Seven Nonpharmacological Interventions on Global Cognition in Older Adults with and without Mild Cognitive Impairment: A Network Meta-Analysis of Randomized Controlled Trials. Scientific Reports, 14, Article No. 8402. [Google Scholar] [CrossRef] [PubMed]
[25] 宋飞云, 丁可欣, 孙雯, 等. COPD家庭肺康复方案改善认知功能的研究进展[J]. 湖北民族大学学报(医学版), 2024, 41(1): 94-98.
[26] 于雅洁. 传统有氧代谢运动对慢性阻塞性肺疾病-阻塞性睡眠呼吸暂停低通气综合征重叠综合征患者认知能力及生活质量的影响[C]//中国体育科学学会. 第十三届全国体育科学大会论文摘要集——墙报交流(运动医学分会) (一). 2023: 18-20.
[27] 刘亚玲. 多元化健康教育对慢性阻塞性肺疾病患者认知功能的影响[J]. 山西卫生健康职业学院学报, 2023, 33(2): 159-160.