中医基于PI3K/Akt/mTOR信号通路治疗类风湿关节炎的研究进展
Research Progress on the Treatment of Rheumatoid Arthritis by Traditional Chinese Medicine Based on the PI3K/Akt/mTOR Signaling Pathway
DOI: 10.12677/acm.2024.14123167, PDF,    科研立项经费支持
作者: 杨 晨*, 袁盛河, 肖世伟：云南中医药大学第一临床医学院，云南 昆明；普勇斌#：云南中医药大学第一附属医院风湿免疫科，云南 昆明
关键词: 类风湿关节炎；中医；PI3K/Akt/mTOR信号通路；研究进展；Rheumatoid Arthritis； Traditional Chinese Medicine； PI3K/Akt/mTOR Signaling Pathway； Research Progress
摘要: PI3K (磷酸肌醇3激酶)/Akt (蛋白激酶B)/mTOR (哺乳动物雷帕霉素靶点)信号通路在类风湿关节炎发病过程中起着重要作用，通过调控PI3K/Akt/mTOR信号通路能够减轻关节炎症，中医药以其多成分、多靶点的特点在类风湿关节炎的治疗中发挥着重要作用，本文简要叙述了近年来中医基于PI3K/Akt/mTOR信号通路治疗类风湿关节炎的研究，以期为类风湿关节炎的治疗及研究提供思路。
Abstract: The PI3K (Phosphoinositide 3-kinase)/Akt (Protein Kinase B)/mTOR (Mammalian Target of Rapamycin) signaling pathway plays a significant role in the pathogenesis of rheumatoid arthritis. Regulating the PI3K/Akt/mTOR signaling pathway can alleviate joint inflammation. Chinese medicine plays a vital role in the treatment of rheumatoid arthritis due to its multi-component and multi-target characteristics. This article briefly describes recent Chinese medicine research on the treatment of rheumatoid arthritis based on the PI3K/Akt/mTOR signaling pathway, aiming to provide ideas for the treatment and research of rheumatoid arthritis.
文章引用：杨晨, 袁盛河, 肖世伟, 普勇斌. 中医基于PI3K/Akt/mTOR信号通路治疗类风湿关节炎的研究进展[J]. 临床医学进展, 2024, 14(12): 916-922. https://doi.org/10.12677/acm.2024.14123167

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