碱性磷酸酶与急性心梗后心室重构的研究进展
Research Progress on Alkaline Phosphatase and Ventricular Remodeling after Acute Myocardial Infarction
DOI: 10.12677/acm.2025.151222, PDF,   
作者: 罗 仙, 袁忠明*:重庆医科大学附属第二医院老年医学科,重庆
关键词: 碱性磷酸酶急性心肌梗死心室重塑Alkaline Phosphatase Acute Myocardial Infarction Ventricular Remodeling
摘要: 心血管疾病已经成为我国居民死亡的首要原因,其中急性心肌梗死(Acute Myocardial Infarction, AMI) 已成为心血管疾病死亡的主要原因之一。急性心肌梗死后心室重塑是心梗后心力衰竭(Heart failure, HF)发生和发展的关键步骤。而碱性磷酸酶(Alkaline Phosphatase, ALP)作为一种广泛分布于人体各组织的酶类,一直在肝胆疾病和骨骼代谢相关疾病的诊断中有着较多的研究,但近年来在心血管疾病中的研究逐渐增多,尤其是在心梗后心室重塑及进一步发生心力衰竭中的作用引起了广泛关注。越来越多的研究证明,碱性磷酸酶与急性心肌梗死后心室重塑及心力衰竭的发生、发展及预后关系紧密。本文就碱性磷酸酶与急性心肌梗死后心室重塑的研究进展进行概述。
Abstract: Cardiovascular diseases have become the primary cause of death among Chinese residents, with acute myocardial infarction (AMI) being one of the main reasons for cardiovascular-related deaths. Ventricular remodeling after acute myocardial infarction is a crucial step in the occurrence and progression of heart failure (HF) post-infarction. Alkaline Phosphatase (ALP), an enzyme widely distributed in various human tissues, has been extensively studied in the diagnosis of hepatobiliary diseases and bone metabolism-related disorders. However, in recent years, research on ALP in cardiovascular diseases has gradually increased, particularly its role in post-infarction ventricular remodeling and the subsequent development of heart failure, which has attracted widespread attention. Increasing studies have demonstrated a close relationship between ALP and the occurrence, development, and prognosis of ventricular remodeling and heart failure following acute myocardial infarction. This article provides an overview of the research progress on ALP in relation to ventricular remodeling after acute myocardial infarction.
文章引用:罗仙, 袁忠明. 碱性磷酸酶与急性心梗后心室重构的研究进展[J]. 临床医学进展, 2025, 15(1): 1654-1662. https://doi.org/10.12677/acm.2025.151222

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