TyG指数与2型糖尿病合并超重肥胖的影响因素分析

Analysis of the Influencing Factors of TyG Index and T2DM Combined with Overweight and Obesity

摘要: 目的：分析成年人甘油三酯葡萄糖乘积(TyG)指数与2型糖尿病(T2DM)伴超重/肥胖状况之间的影响因素。方法：本研究选取60例T2DM伴超重/肥胖的患者组成患病组，同时选取30名健康个体构成健康对照组。收集两组的基本信息、检验参数指标，行统计学分析。结果：健康组与患病组在TyG指数、甘油三酯水平(TG)、空腹血糖值(FPG)、体重指数(BMI)、糖化血红蛋白(HbA1c)、红细胞计数(RBC)及空腹C肽浓度(FCP)等指标方面有显著差异。TyG指数、BMI的升高以及HbA1c的上升伴随RBC的下降，是T2DM伴超重/肥胖的独立风险因素。ROC曲线下面积(AUC)为0.841。结论：TyG指数在T2DM伴超重/肥胖人群的诊断与预测中发挥着重要作用。

Abstract: Objective: To analyze the influencing factors between adult triglyceride glucose product (TyG) index and type 2 diabetes mellitus (T2DM) with overweight and obesity. Methods: In this study, 60 patients with T2DM with overweight and obesity were selected to form the disease group, and 30 healthy individuals were selected to form the healthy control group to collect basic information of the two groups. The parameters were tested and the difference was compared by binary and multi-factor Logistic regression ROC curve. Results: TyG index, triglyceride level (TG), fasting blood glucose value (FPG), body mass index (BMI), glycosylated hemoglobin (HbA1c) in the healthy group and the diseased group. There were significant differences in red blood cell count (RBC) and fasting C-peptide concentration (FCP), and the increase of TyG BMI and HbA1c were accompanied by the decrease of RBC. The area under ROC curve (AUC) of T2DM with overweight and obesity was 0.841. Conclusion: TyG index plays an important role in the diagnosis and prediction of T2DM patients with overweight and obesity.