雌激素及雌激素受体在SPID-CPP炎症过程的研究进展

Advances in the Study of Estrogen and Estrogen Receptors in the Inflammatory Process of SPID-CPP

摘要: 盆腔炎性疾病后遗症(sequelae of pelvic inflammatory disease, SPID)——慢性盆腔痛(chronic pelvic pain, CPP)是以各种器质性和(或)功能性原因引起的盆腔及其周围组织疼痛反复发作为主要症状，持续时间超过6个月的综合征。近年来研究显示SPID-CPP的炎症过程中雌激素水平表达异常。本文对近年来相关文献进行汇总，探讨雌激素及其受体在参与SPID-CPP的炎症过程中的机制及途径。

Abstract: Sequelae of pelvic inflammatory disease (SPID)—Chronic pelvic pain (CPP) is a recurrent pelvic and peripheral tissue pain of various organic and/or functional causes, lasting more than 6 months, as the main symptom. Syndrome. Recent studies have shown that SPID-CPP expresses abnormal estrogen levels during the inflammatory process. In this paper, we summarize the relevant literature in recent years to explore the mechanisms and pathways of estrogen and its receptors in participating in the inflammatory process of SPID-CPP.