脾切除术后急性感染性暴发性紫癜的治疗及文献回顾
Treatment and Literature Review of Acute Infectious Purpura Fulminans after Splenectomy
DOI: 10.12677/jcpm.2025.41109, PDF,   
作者: 王 娟*, 左和平, 夏子君, 李景荣#：安徽医科大学第二附属医院急诊重症监护室，安徽 合肥
关键词: 暴发性紫癜(PF)；脾切除；急性感染；Purpura Fulminans (PF)； Splenectomy； Acute Infection
摘要: 目的：探讨脾切除后急性感染性暴发性紫癜(AIPF)的临床症状、体征及辅助检查指标等的变化，为此疾病的诊断与治疗提供参考方案。方法：回顾本科室2019年12月23日收治的1例患者的病历、临床表现、体征、实验室检查结果及诊治经过等，结合数据库中以“暴发性紫癜”与“脾切除”及“fulminant purpura”与“splenectomy”检索获得的相似病例，分析以及比较其临床特征、治疗过程以及预后，探讨可能的诊疗和防治措施。结论：肺炎链球菌导致急性感染性暴发性紫癜(AIPF)的发育免疫功能缺陷，如脾切除或者脾功能低下患者，早期识别和治疗能够改善患者预后。
Abstract: Objective: To investigate the changes in the clinical symptoms, signs and auxiliary examination indicators of acute infectious fulminant purpura (AIPF) after splenectomy, and to provide a reference plan for the diagnosis and treatment of this disease. Methods: The medical records, clinical manifestations, signs, laboratory test results, diagnosis and treatment process of one patient admitted to our department on December 23, 2019 were reviewed, combined with the similar cases retrieved by “fulminant purpura” and “splenectomy” in the database, the clinical characteristics, treatment process and prognosis were analyzed and compared, and the possible diagnosis and treatment measures were discussed. Conclusion: Streptococcus pneumoniae causes acute infectious fulminant purpura (AIPF) and is good for developmental immune deficiencies, such as splenectomy or hyposplenism, and early recognition and treatment can improve the prognosis of patients.
文章引用：王娟, 左和平, 夏子君, 李景荣. 脾切除术后急性感染性暴发性紫癜的治疗及文献回顾[J]. 临床个性化医学, 2025, 4(1): 770-778. https://doi.org/10.12677/jcpm.2025.41109

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