中国医院药物警戒系统在ADE主动监测方面的研究进展
Research Progress of Chinese Hospital Pharmacovigilance System in Active ADE Monitoring
DOI: 10.12677/acm.2025.153660, PDF,   
作者: 姚凯云, 魏 翼：大理大学药学院，云南 大理；林意菊*：大理市第一人民医院医务部，云南 大理；华敏凡：中国人民解放军联勤保障部队第九二六医院药剂科，云南 开远
关键词: 中国药物警戒系统；药品不良反应主动监测；研究进展；China Pharmacovigilance System； Active Monitoring of Adverse Drug Reaction； Research Progress
摘要: 随着人工智能(AI)技术的飞速发展，以及大量以电子方式存储的药物不良事件(ADE)相关数据的不断出现，迫切需要将电子数据驱动的药物不良事件自动化监测方法应用于药物警戒的各个方面，以协助医护人员日常的工作。据最新研究证实，对比分析中国医院药物警戒系统(CHPS)和传统药品不良反应自发呈报系统(ADR)，其具有天然的药物不良事件主动监测及真实世界研究优势，不仅能弥补传统药物不良反应主动监测过程中存在的漏报率高、及时性差、报告质量差等一系列问题，且由于CHPS直接对接的是国家药品不良反应监测系统，还可以减少上报过程中一系列繁琐的步骤。
Abstract: With the rapid development of Artificial Intelligence (AI) technology and the emergence of a large amount of electronically stored data related to Adverse Drug Events (ADEs), there is an urgent need to apply electronic data-driven automated ADE monitoring methods to all aspects of pharmacovigilance in order to assist healthcare professionals in their daily work. According to the latest research, comparative analyses of the Chinese Hospital Pharmacovigilance System (CHPS) and the traditional Adverse Drug Reaction Reporting System (ADRA) have the natural advantages of active monitoring of adverse drug events and real-world research, which not only can make up for a series of problems such as high underreporting rate, poor timeliness, and poor quality of reports that existed in the process of the traditional active monitoring of ADE, but also, because CHPS is directly connected to the National Adverse Drug Reaction Monitoring System, it can reduce a series of cumbersome steps in the reporting process.
文章引用：姚凯云, 林意菊, 华敏凡, 魏翼. 中国医院药物警戒系统在ADE主动监测方面的研究进展[J]. 临床医学进展, 2025, 15(3): 651-657. https://doi.org/10.12677/acm.2025.153660

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