儿童迁延性细菌性支气管炎的呼吸道微生物群特征研究进展
Research Progress of the Respiratory Microbiome Characteristics in Children with Protracted Bacterial Bronchitis
DOI: 10.12677/acm.2025.153733, PDF,   
作者: 覃欣蕊, 代继宏*：重庆医科大学附属儿童医院呼吸科/儿童发育疾病研究教育部重点实验室/国家儿童健康与疾病临床医学研究中心/儿童发育重大疾病国家国际科技合作基地/儿科学重庆市重点实验室，重庆
关键词: 迁延性细菌性支气管炎；微生物组；生物膜；Protracted Bacterial Bronchitis； Microbiome； Biofilm
摘要: 迁延性细菌性支气管炎(protracted bacterial bronchitis, PBB)是引起儿童慢性咳嗽的常见病因，目前对其呼吸道微生物群特征研究关注度较高，探索影响PBB进展及复发的相关PBB类型。本文就儿童迁延性细菌性支气管炎的下呼吸道微生物群特征、生物膜及微生物间的相互作用的研究进展进行总结，以期为PBB患儿提供个体化的医疗策略。
Abstract: Protracted bacterial bronchitis (PBB) is a common cause of chronic cough in children. Currently, studies have focused on the characteristics of respiratory microbiota and explored the related PBB endotypes that affect the progress and recurrence of PBB. This article reviews the research progress of lower respiratory tract microbiota characteristics, biofilm, and microbial interactions in children with protracted bacterial bronchitis, in order to provide personalized medical strategies for children with PBB.
文章引用：覃欣蕊, 代继宏. 儿童迁延性细菌性支气管炎的呼吸道微生物群特征研究进展[J]. 临床医学进展, 2025, 15(3): 1236-1242. https://doi.org/10.12677/acm.2025.153733

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